摘要
目的：观察和分析对精神分裂症患者分别采用富马酸喹硫平以及奥氮平进行治疗的临床情况和效果。方法：随机择选58例精神分裂症患者，平分为对照组（奥氮平）和观察组（富马酸喹硫）进行治疗，并就两组患者的临床诊治效果进行统计学比较和分析。结果：观察组的临床总有效率（93.10%）略高于对照组（89.66%），但两组比较的差异性不大（P>0.05）。不良反应率（17.24%）明显少于对照组（65.52%），比较具有统计学意义（P<0.05）。结论：采用富马酸喹硫平与奥氮平对精神分裂症患者进行临床诊治，其疗效均较好，但富马酸喹硫平的不良反应更少，安全性更高，因此，应该作为临床治疗的首选方法。
Abstract
Objective: To observe and analyze the clinical effects of olanzapine and quetiapine fumarate in the treatment of schizophrenia. Methods: 58 patients who were treated with schizophrenia in our hospital were divided into a control group ( olanzapine) and an observation group ( quetiapine fumarate) , with 29 patients in each group. Patients in the control group were treated with quetiapine fumarate and those in the observation group were treated with olanzapine. Then the therapeutic ef-fects of the two groups were statistically compared and analyzed. Results: total efficiency of the observation group (93.1%) is slightly higher than that of the control group (89.66%) , but there is little difference found of the two groups (P>0.05) . With the adverse reaction incidence of 17.24%, the observation group is remarkably better than the control group's 65.52%and it has statistical significance (P<0.05) . Conclusion:Olanzapine and quetiapine fumarate have remarkable clinical effects in the treat-ment of schizophrenia, but patients have fewer adverse reactions with the treatment of quetiapine fumarate. Besides, it can en-sure the security. Therefore, it should be used as the preferred method for the treatment of schizophrenia.
NETL
NSTL
维普
万方数据