摘要
目的：分析研究幽门螺旋杆菌（HP）阳性与相关肿瘤标志物相关性。方法选取于2014年5月—2015年5月期间来院治疗的肺癌患者36例作为观察组，选取同期来院体检中心的健康体检人员30例作为对照组，均进行血清幽门螺旋杆菌血清学抗体及幽门螺杆菌细胞毒素相关蛋白抗体检测。结果观察组的Hp-IgG阳性率、Hp-CagA-IgG阳性率分别为94.44%、91.67%，对照组Hp-IgG阳性率、Hp-CagA-IgG分别为53.33%、23.33%，差异有统计学意义（P<0.05）。结论幽门螺旋杆菌阳性与肺癌的发生密切相关，鳞癌的平均HP-IgG水平较腺癌、小细胞癌高。
Abstract
Objective:To analyze the correlation between the positive expression of Helicobacter pylori (HP) and tumor markers. Methods:36 patients with lung cancer who were treated in the hospital from January 2013 to January were selected as the observation group, and 30 cases of healthy persons were selected as the control group. Results:The positive rate of Hp-IgG in the observation group were 94.44%and 91.67%, respectively, Hp-IgG positive rate of the control group, Hp-CagA-IgG were 53.33%, 23.33%, the difference was statistically significant (P<0.05). Conclusion:The positive expression of Helicobacter pylori is closely related to the occurrence of lung cancer, the average HP-IgG level of squamous cell carcinoma is higher than that of adenocarcinoma and small cell carcinoma.
NETL
NSTL
维普
万方数据