"怪病多痰"病机观下抑郁症与慢性疲劳综合征的相关性
Correlation Between Depression and Chronic Fatigue Syndrome under the Concept of"Strange Disease is Related to Phlegm"
门奕年 1黄珍 1于明直 1许心奕 1雷超芳 1刘玥芸 1陈家旭1
作者信息
- 1. 北京中医药大学中医学院,北京,100029
- 折叠
摘要
抑郁症与慢性疲劳综合征是在症状上存在相似性,在发病机制上有潜在关联,并具有共同候选生物标志物和各自独特差异代谢物的异质性疾病.现聚焦抑郁症与慢性疲劳综合征的相似点,以"怪病多痰"为切入点,痰气交阻是二者相关的病机核心,脏腑功能失调-气机不利-化生痰浊-阻滞气机-伤及脏腑是二者的共同发病过程.在抑郁症与慢性疲劳综合征的研究和临证中,应重点关注"痰"与"气"的互作关系,以期更有效地将中医异病同治优势运用于慢性疑难性疾病的防治,并丰富其理论内涵.
Abstract
Depression and chronic fatigue syndrome are heterogeneous disorders that share similarities in symptoms and common candidate biomarkers,with unique differential metabolites.They have potential associations in pathogenesis mechanism.This paper focused on the similar characteristics of depression and chronic fatigue syndrome,and took"strange disease is related to phlegm"as the entry point.It was believed that phlegm-qi mutual obstruction was the common pathogenesis of these two diseases,and dys-function of zang-fu organs-disorder of qi movement-turbid phlegm formation-blockage of qi movement-damage of zang-fu organs is the common disease pathway.In the research and clinical work of depression and chronic fatigue syndrome,we should emphasize the mutual relationship between"phlegm"and"qi",to give full play of the advantages of traditional Chinese medicine in treating different diseases with the same method in the prevention and treatment of difficult chronic diseases and enrich the theoretical con-notation.
关键词
怪病多痰/抑郁症/慢性疲劳综合征/痰证/精神障碍/躯体障碍/异病同治/痰气交阻Key words
Strange disease is related to phlegm/Depression/Chronic fatigue syndrome/Phlegm syndrome/Mental disorder/So-matic disorder/Treating different diseases with the same method/Phlegm-qi mutual obstruction引用本文复制引用
基金项目
国家自然科学基金面上项目(82174278)
北京市自然科学基金面上项目(7212182)
出版年
2023
国家科技期刊平台
NSTL
万方数据