中医正邪理论与抑癌基因和癌基因在肿瘤中的相关性
Role of Cancer-related Genes in Tumors From the Theory of Healthy Qi and Pathogenic Qi in Traditional Chinese Medicine
顾知恩 1王磊 1陈悦 2翟嘉威 2洪专 3杨宇飞1
作者信息
- 1. 中国中医科学院西苑医院肿瘤诊疗中心,北京,100091
- 2. 北京中医药大学,北京,1000291
- 3. 江苏省肿瘤医院,南京,210009
- 折叠
摘要
正邪理论是中医认识疾病的基本模型之一,其中蕴含有对立统一的哲学思想.肿瘤的发生发展与基因突变相关,抑癌基因与癌基因在分子层面上的行为可以作为一种症状纳入正邪理论体系中.分析抑癌基因与癌基因在肿瘤发生、发展中表现出的正邪关系,有利于将现代医学的研究结论与中医基础理论相联系,从而扩充正邪理论的内涵,以期为肿瘤的中医治疗提供更多证据支撑.
Abstract
The theory of healthy qi and pathogenic qi is a basic model for understanding diseases in traditional Chinese medicine(TCM),which implies the philosophical thought of the contradictory unity.The occurrence and development of tumors is closely re-lated to genetic mutation,and the behaviors of antioncogenes and oncogenes at the molecular level can be considered as symptoms and summarized into the theory of healthy qi and pathogenic qi.This paper analyzed the relationship between healthy qi and patho-genic qi demonstrated by antioncogenes and oncogenes in the occurrence and development of tumors,which is conducive to connect-ing the research findings of modern medicine with the basic TCM theory and expanding the theoretical connotation of healthy qi and pathogenic qi.It is expected to provide evidence for the TCM treatment of tumors.
关键词
正邪理论/恶性肿瘤/原癌基因/抑癌基因/癌基因/相关性/中医治疗/基因突变Key words
Theory of healthy qi and pathogenic qi/Malignant tumor/Proto-oncogene/Antioncogene/Oncogene/Correlation/Traditional Chinese medicine treatment/Gene mutation引用本文复制引用
基金项目
国家自然科学基金面上项目(81373824)
国家中医药管理局"十三五"重大疑难疾病中西医临床协作试点项目(国中医药办医政函[2018]275)
出版年
2023
国家科技期刊平台
NSTL
维普
万方数据