细胞焦亡对肝癌发生发展的影响及中医药的干预作用
Influence of Pyroptosis on the Development of Hepatocellular Carcinoma and the Intervention with Traditional Chinese Medicine
杨润瑞 1王勇 2段柳剑 1柯尊丽1
作者信息
- 1. 贵州中医药大学,贵阳,550000
- 2. 贵州中医药大学,贵阳,550000;中国科学院分子植物科学卓越创新中心中国科学院合成生物学重点实验室,上海,200000
- 折叠
摘要
细胞焦亡是一种新发现的程序性细胞死亡方式,在肝癌中发挥着关键作用.故拟基于细胞焦亡的分子机制及其在肝癌发病机制中的作用进行深入分析,并结合中医药在调节焦亡肝癌发展过程中的作用进行探讨,以期为临床提供新的治疗思路.
Abstract
Pyroptosis is a newly discovered mode of programmed cell death that plays a key role in hepatocellular carcinoma.This paper probes into the molecular mechanism of pyroptosis and its role in the pathogenesis of hepatocellular carcinoma,and discusses the role of traditional Chinese medicine in regulating pyroptosis to curb the development of hepatocellular carcinoma,with a view to providing new therapeutic ideas for clinical practice.
关键词
肝癌/肿瘤/炎症小体/细胞死亡/细胞焦亡/中医药/分子机制/研究进展Key words
Hepatocellular carcinoma/Tumor/Inflammasome/Cell death/Pyroptosis/Traditional Chinese medicine/Molecular mechanism/Research progress引用本文复制引用
基金项目
国家自然科学基金地区基金(82060797)
贵州省科技创新人才团队(黔科合平台人才[2020]5010)
贵州省发改委工程研究中心建设项目(黔发改高技[2020]896号)
出版年
2023