穴区结缔组织在针刺效应启动中的作用机制研究进展
Research Progress on the Role and Mechanism of Connective Tissue in the Initiation of Acupuncture Effects in Acupoint Areas
付疆疆 1林小伟 2窦报敏 1李艳伟 1樊泽至 1刘琪 1郭义3
作者信息
- 1. 天津中医药大学针灸推拿学院,天津,301617
- 2. 天津中医药大学实验针灸学研究中心,天津,301617;天津中医药大学中医学院,天津,301617
- 3. 天津中医药大学实验针灸学研究中心,天津,301617
- 折叠
摘要
穴区作为针刺的初始应答部位,是针效的源头.针刺引起穴区微环境的变化是其发挥效应的关键启动环节,阐明针刺的启动机制可进一步推动针刺临床应用.通过对针刺穴区相关基础研究文献进行梳理,发现针刺后穴区微环境结缔组织的变化与针刺效应密切相关,结缔组织中成纤维细胞、肥大细胞和巨噬细胞在针刺效应启动过程中发挥了重要作用,但有关针刺穴位启动机制的基础研究零散、不系统,针刺穴位启动机制的研究可为针刺临床应用提供依据,未来仍有很大深入研究的空间.
Abstract
The acupoint area,as the initial response site to acupuncture,is the origin of acupuncture effect.The change in the acu-point microenvironment caused by acupuncture is the key initiating step for the manifestation of its effect.Clarifying the initiation mechanism of acupuncture can further promote the clinical application of acupuncture.Through a review of relevant research litera-ture on acupoint acupuncture,this paper finds that the changes in connective tissue in the acupoint microenvironment are closely re-lated to acupuncture effect,and fibroblasts,mast cells and macrophages within the connective tissue play an important role in the in-itiation of acupuncture effect.However,the basic research on the initiation mechanism of acupuncture at acupoint sites is scattered and not systematic.Further in-depth research on the initiation mechanism of acupuncture at acupoint sites can provide a basis for the clinical application of acupuncture.There is still considerable room for future exploration and research in this area
关键词
针刺/穴区/结缔组织/针刺效应/穴区微环境/成纤维细胞/肥大细胞/巨噬细胞Key words
Acupuncture/Acupoint area/Connective tissue/Acupuncture effect/Acupoint microenvironment/Fibroblasts/Mast cells/Macrophages引用本文复制引用
基金项目
国家自然科学基金重点基金(82030125)
国家自然科学基金青年科学基金(82105024)
天津市科技计划项目(20JCQNJC00280)
天津市卫生健康委员会青年项目(2021056)
出版年
2023
国家科技期刊平台
NSTL
维普
万方数据