首页|中药复方治疗腰椎间盘突出症的临床随机对照试验证据图

中药复方治疗腰椎间盘突出症的临床随机对照试验证据图

Evidence of Clinical Randomized Controlled Trials in Treatment of Lumbar Disc Herniation with Traditional Chinese Medicine Decoctions

扫码查看
原文链接
  • 国家科技期刊平台
  • NETL
  • NSTL
  • 维普
  • 万方数据
目的:通过系统检索并梳理中药复方治疗腰椎间盘突出症(LDH)临床随机对照试验(RCT),了解该领域的证据分布.方法:检索国家知识基础设施数据库(CNKI)、中文科技期刊数据库(CCD)、中文科技期刊数据库(CCD)、中国生物医学文献数据库(CBM)、PubMed、Embase、Cochrane图书馆、Web of Science数据库中的文献,检索时间限定为2013年1月至2023年2月,纳入相关中药复方治疗LDH的RCT,以文字和图表相结合的方式呈现证据的分布情况.结果:共纳入102项临床研究,文献发表数量总体呈逐渐上升的趋势;疗程多为1～4周;方法学质量评价结果显示目前中药复方治疗LDH的临床研究质量较低;中药治疗LDH对疼痛类指标、功能障碍指标、临床疗效、安全性指标等方面关注较多,而对于中医证候评分/中医症状积分、影像学指标、血液检测指标、生命质量指标、经济学指标及复发率方面关注较少.结论:中药复方在治疗LDH上具有独特优势,但是也存在局限性,中药复方治疗LDH临床研究质量较低,未来需进一步提高临床随机对照试验研究质量,为中药复方防治LDH的有效性及安全性提供更充分的证据支持.
Objective:To systematically sort out the clinical randomized controlled trials(RCTs)of treating lumbar disc herniation(LDH)with traditional Chinese medicine(TCM)decoctions by using the method of evidence map,and to understand the distribu-tion of evidence in this field.Methods:The RCTs involving TCM decoctions for LDH were retrieved from the China National Knowledge Infrastructure(CNKI),Chinese Citation Database(CCD),China Biology Medicine(CBM),PubMed,Embase,Cochrane Library,and Web of Science,with the time interval from January 2013 to February 2023.The distribution of evidence was presented in a combination of text and graphs.Results:A total of 102 clinical studies were included,and the overall number of publications showed an increasing trend over time.The treatment courses ranged from 1 to 4 weeks.The results of methodological quality evalua-tion showed that the current clinical studies of TCM decoctions for LDH were of low quality.These studies cared more about the in-dicators of pain,functional impairment,clinical efficacy,safety,and less about TCM syndrome/symptom scores and indicators of im-aging,blood test,quality of life,economy,and recurrence.Conclusion:TCM decoctions have unique advantages in the treatment of LDH,while they also have limitations.The clinical studies on the treatment of LDH with TCM decoctions have low quality.The clin-ical RCTs remain to be improved in quality,so as to provide adequate evidence to support the effectiveness and safety of TCM de-coctions in the prevention and treatment of LDH.

Lumbar disc herniationTraditional Chinese medicine decoctionClinical studyRandomized controlled trialsEvi-dence mapResearch statusMethodologyQuality assessment

肖想玉、秦晓宽、杨克新、魏戌、孙凯、朱立国

展开 >

山东中医药大学第一临床医学院,济南,250355

中国中医科学院望京医院,北京,100102

中医正骨技术北京市重点实验室,北京,100102

腰椎间盘突出症 中药复方 临床研究 随机对照试验 证据图 研究现状 方法学 质量评价

国家重点研发计划项目国家重点研发计划项目国家自然科学基金青年科学基金中国中医科学院科技创新工程项目中国中医科学院优秀青年科技人才课题

2021YFC17128002021YFC171280382205152CI2021A02004ZZ16-YQ-023

2023

10.3969/j.issn.1673-7202.2023.21.003

世界中医药
世界中医药学会联合会

世界中医药

CSTPCDCHSSCD北大核心
影响因子：1.266
ISSN：1673-7202
年,卷(期)：2023.18(21)
  • 18