首页|从"微生物-脑-肠轴"谈中医"脑肠同治"防治结直肠癌

从"微生物-脑-肠轴"谈中医"脑肠同治"防治结直肠癌

Prevention and Treatment of Colorectal Cancer by Simultaneous Treatment of Brain and Gut in Traditional Chinese Medicine Based on Microorganism-gut-brain Axis

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  • 国家科技期刊平台
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  • NSTL
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结直肠癌(CRC)是我国发病率和死亡率较高的消化道恶性疾病之一,"微生物-脑-肠轴"包括肠道菌群微生物及其代谢产物、肠神经系统、自主神经系统、神经免疫学、神经内分泌系统和中枢神经系统,"微生物-脑-肠轴"在CRC肿瘤细胞的生长、增殖、侵袭和转移方面起重要作用.中医药凭借中医思维优势,以中医整体观认识CRC,脑肠同治,在脑-心-神及肠-脾-肝2个方面对机体进行调节,维持"微生物-脑-肠轴"的相对平衡,进而防治结直肠癌.
Colorectal cancer(CRC)is one of the malignant diseases of the digestive tract,with high morbidity and mortality in China.The microorganism-gut-brain axis includes gut flora and their metabolites,enteric nervous system,autonomic nervous system,neuroimmune system,neuroendocrine system,and central nervous system.It plays an important role in the growth,proliferation,in-vasion,and metastasis of CRC cells.According to the holistic view of traditional Chinese medicine(TCM),CRC can be treated from both the brain and the gut.The balance of the microorganism-gut-brain axis can be maintained by regulating the intestinal flora,which can inhibit the progression of CRC.

Colorectal cancerIntestinal floraBrain-gut axisSimultaneous treatment of brain and gutTraditional Chinese med-icineStaging treatmentPrecancerous lesionsMicroorganisms

王欣妍、王烁、曹康迪、樊芬、侯炜

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北京中医药大学研究生院,北京,100029

中国中医科学院广安门医院,北京,100053

结直肠癌 肠道菌群 脑-肠轴 脑肠同治 中医药 分期治疗 癌前病变 微生物

国家自然科学基金中国中医科学院科技创新工程重大攻关项目

8207142125CI2021A01801

2023

10.3969/j.issn.1673-7202.2023.21.015

世界中医药
世界中医药学会联合会

世界中医药

CSTPCDCHSSCD北大核心
影响因子：1.266
ISSN：1673-7202
年,卷(期)：2023.18(21)
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