首页|基于"寒气生浊"理论探微癌性疼痛的机制与治疗

基于"寒气生浊"理论探微癌性疼痛的机制与治疗

Mechanism and Treatment of Cancer Pain Based on the Theory of"Cold Qi Generates Turbidity"

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  • 国家科技期刊平台
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癌性疼痛为癌症中晚期患者最常见、最痛苦的症状之一,也是临床上待解决的难题之一.癌性疼痛发病机制复杂,目前仍沿用世界卫生组织颁布的三阶梯止痛方案,但治疗效果不理想.近年来,中西医结合治疗癌性疼痛的研究越来越广泛,且效果较佳.现基于《黄帝内经》中"寒气生浊"理论为核心,探微癌性疼痛微环境发病机制,提出整体以扶正培本为先,止痛以通阳调气为要,局部以通络化浊为主辨治癌性疼痛治疗思路,兼顾整体与局部治疗方案,为治疗癌性疼痛提供了可靠的理论依据和研究思路.
Cancer pain is one of the most common and painful symptoms for patients with mid-to late-stage cancer,and it is also one clinical challenge to be solved.The pathogenesis of cancer pain is complex,and the three-step analgesic ladder promulgated by WHO is still being used,with unsatisfactory treatment effect.In recent years,studies on the treatment of cancer pain with integrative Chinese and western medicine have become wider and wider and shown desirable results.According to the theory of"cold qi gener-ates turbidity"in Huangdi Neijing(Huangdi's Internal Classic),this paper explored the microenvironmental pathogenesis of cancer pain,and proposed the idea of syndrome differentiation and treatment.In other words,the overall treatment should be based on rein-forcing healthy qi and cultivating root;the pain relief should be based on tonifying yang and regulating qi;the local treatment should be based on dredging collaterals and resolving turbidity.This idea involves simultaneous treatment of the whole body and the local area,which provides a reliable theoretical basis for the treatment of cancer pain.

Cancer painReinforcing healthy qi and consolidating rootTheory of cold qi generates turbidityMechanismTreat-mentCancer microenvironmentPathogenesis of traditional Chinese medicineExternal treatment of traditional Chinese medicine

阿依达娜·毛兰、刘瑞、花宝金

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北京中医药大学研究生院,北京,100029

中国中医科学院广安门医院肿瘤科,北京,100053

癌性疼痛 扶正培本 寒气生浊 作用机制 治疗 肿瘤微环境 中医病机 中医外治法

国家自然科学基金国家自然科学基金国家自然科学基金国家中医药局中医药创新团队及人才支持计划中国中医科学院科技创新工程项目中国中医科学院科技创新工程项目

822746098207433882174465ZYYCXTD-C-202205CI2021A01810CI2021B009

2023

10.3969/j.issn.1673-7202.2023.22.011

世界中医药
世界中医药学会联合会

世界中医药

CSTPCDCHSSCD北大核心
影响因子：1.266
ISSN：1673-7202
年,卷(期)：2023.18(22)
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