Objective:This paper analyzed the current situation and research hotspots of brain-gut axis theory in the field of tradi-tional Chinese medicine in the treatment of irritable bowel syndrome(IBS)and clarified the development trend of the field,so as to provide ideas and basis for the clinical and basic research of traditional Chinese medicine in the treatment of IBS.Methods:Re-search literature on the treatment of IBS with brain-gut axis theory in the field of traditional Chinese medicine published in the CNKI database was searched and collected.The retrieval time was from 2000 to 2021.CiteSpace software was used to visually ana-lyze the authors,institutions,and keywords in the selected literature.Results:Finally,176 pieces of literature meeting the require-ments are included,and the annual volume of publication is gradually increasing;Wu Haomeng,Huo Qingping,Chu Haoran,and Wang Yinghan are the research teams that make the greatest contribution to this field;Nanjing University of Traditional Chinese Medicine,Guangzhou University of Traditional Chinese Medicine,and Shandong University of Traditional Chinese Medicine are the institutions with the largest volume of publication.Research hot words include brain-gut peptide,5-hydroxytryptamine,Tongxie Yao-fang,liver depression and spleen deficiency,etc;the research content focuses on traditional Chinese medical therapy,experimental and mechanism research,and treatment methods and prescriptions.Conclusion:In the past 20 years,the research on the treatment of IBS with brain-gut axis theory in the field of traditional Chinese medicine has made outstanding achievements.At present,the re-search focus is to summarize the clinical experience and improve the curative effect of IBS with traditional Chinese medical therapy.The research trend is to regulate brain-gut peptide and intestinal microecology.
关键词
脑-肠轴/肠易激综合征/中医药/可视化分析/痛泻要方/肝郁脾虚/5-羟色胺/脑-肠肽
Key words
Brain-gut axis/Irritable bowel syndrome/Traditional Chinese medicine/Visual analysis/Tongxie Yaofang/Liver de-pression and spleen deficiency/5-hydroxytryptamine/Brain-gut peptide