世界中医药2023,Vol.18Issue(24) :3616-3620.DOI:10.3969/j.issn.1673-7202.2023.24.025

从络病理论论治糖尿病骨质疏松症的发病机制

Exploring the Pathogenesis of Diabetic Osteoporosis from the Perspective of Collateral Disease Theory

张亚奇 秦灵灵 白惠中 徐林 左心玮 蒋昇源 赵毅 穆晓红
世界中医药2023,Vol.18Issue(24) :3616-3620.DOI:10.3969/j.issn.1673-7202.2023.24.025

从络病理论论治糖尿病骨质疏松症的发病机制

Exploring the Pathogenesis of Diabetic Osteoporosis from the Perspective of Collateral Disease Theory

张亚奇 1秦灵灵 2白惠中 1徐林 1左心玮 1蒋昇源 1赵毅 1穆晓红1
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作者信息

  • 1. 北京中医药大学东直门医院,北京,100700
  • 2. 北京中医药大学,北京,100029
  • 折叠

摘要

糖尿病骨质疏松症西医发病机制为高血糖状态下的骨组织生理结构和代谢功能异常,包括长期高血糖、血管损伤及血液循环障碍、脂代谢异常和体内激素水平失调.结合吴以岭教授中医络病学中"气络病变之内分泌功能失调和脉络病变之微循环障碍"理论,可将糖尿病骨质疏松症中医基本病机归纳为脾肾亏虚、脉络瘀阻、骨络失养,最终导致本病的发生和发展.

Abstract

Diabetic osteoporosis in western medicine is characterized by abnormal physiological structure and metabolic function of bone tissue under a hyperglycemic state,including prolonged hyperglycemia,vascular damage and blood circulation dysfunction,lip-id metabolism abnormalities and hormonal imbalances.Combined with Professor WU Yiling's theory of"endocrine dysfunction in Qi-collateral pathology and microcirculation disorders in vascular-collateral pathology"in traditional Chinese medicine(TCM),the basic TCM pathogenesis of diabetic osteoporosis can be summarized as spleen and kidney deficiency,obstruction of collaterals,bone-collaterals malnourishment,eventually leading to the occurrence and development of the disease.

关键词

糖尿病骨质疏松症/骨络构效失常/络病理论/脾肾亏虚/脉络瘀阻/发病机制

Key words

Diabetic osteoporosis/Bone-collateral structural abnormalities/Collateral disease theory/Spleen and kidney deficien-cy/Obstruction of collaterals/Pathogenesis

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基金项目

国家自然科学基金(81874467)

北京市自然科学基金(L192059)

出版年

2023
世界中医药
世界中医药学会联合会

世界中医药

CSTPCDCHSSCD北大核心
影响因子:1.266
ISSN:1673-7202
参考文献量23
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