Alzheimer's disease is the most common neurodegenerative disease,and its etiology and pathogenesis are still unclear.Currently,effective treatment drugs and methods are lacking.Microglia,as the innate immune cells of the central nervous system,play a central role in mediating neuroinflammation in the pathogenesis of Alzheimer's disease.Activation of autophagy can reduce neuronal apoptosis and inhibit neuroinflammation.Acupuncture has a significant therapeutic effect on Alzheimer's disease and has a regulatory effect on microglia,which can inhibit central inflammation,activate autophagy,and regulate synaptic plasticity.
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