世界中医药2024,Vol.19Issue(2) :272-278.DOI:10.3969/j.issn.1673-7202.2024.02.023

商陆提取物药理作用研究进展

Research Progress in Pharmacological Action of Phytolacca Acinosa Extract

徐静 李晓亮 高宁 王宇 匡海学 梁华
世界中医药2024,Vol.19Issue(2) :272-278.DOI:10.3969/j.issn.1673-7202.2024.02.023

商陆提取物药理作用研究进展

Research Progress in Pharmacological Action of Phytolacca Acinosa Extract

徐静 1李晓亮 2高宁 3王宇 3匡海学 3梁华3
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作者信息

  • 1. 黑龙江中医药大学,哈尔滨,150040;黑龙江中医药大学附属第一医院,哈尔滨,150040
  • 2. 海南医学院,海口,571199
  • 3. 黑龙江中医药大学,哈尔滨,150040
  • 折叠

摘要

商陆是我国传统峻下逐水中药,收载于历版《中华人民共和国药典》,入药部位为根部,具有利尿泻下、抗炎、抗肿瘤、祛痰镇咳平喘等药理活性.临床多用于治疗肾炎、肝硬化腹水、乳腺增生、银屑病等疾病.通过对商陆提取物和化学成分药理作用进行总结,为今后商陆深入研究及合理开发利用提供支持和参考依据.

Abstract

Phytolacca acinosa is a traditional Chinese medicine for expelling water by purgation,which is recorded in the Pharma-copoeia of the People's Republic of China.The medicinal part of Phytolacca acinosa is the root,which has pharmacological activities such as diuresis and purgation,anti-inflammatory,anti-tumor,dispelling phlegm,and relieving cough and asthma.Phytolacca acinosa is mainly used to treat nephritis,cirrhosis ascites,hyperplasia of mammary gland,psoriasis and other diseases.This paper summari-zes the pharmacological effects of phytolacca acinosa extract and its chemical components.It provides support and reference for fur-ther research and rational development and utilization of Phytolacca acinosa in the future.

关键词

商陆/药理作用/三萜皂苷/多糖/抗炎/氧化应激/信号通路/促分裂原活化的蛋白激酶

Key words

Phytolacca acinosa/Pharmacological action/Triterpenoid saponin/Polysaccharide/Anti-inflammatory/Oxidative stress/Signaling pathway/Mitogen-activated protein kinase

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基金项目

国家重点基础研究发展计划(973计划)(2013CB531801)

国家自然科学基金(81473563)

黑龙江省中医药经典普及化专项(ZYW2023-003)

黑龙江省自然科学基金(JJ2022LH1048)

黑龙江中医药大学科研项目(2018jkcy06)

出版年

2024
世界中医药
世界中医药学会联合会

世界中医药

CSTPCDCHSSCD北大核心
影响因子:1.266
ISSN:1673-7202
参考文献量61
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