Clinical Efficacy of Acupuncture at Back-shu and Front-mu Acupoints in Treating Depression of Liver Depression and Spleen Deficiency Syndrome
Objective:To observe the clinical efficacy of acupuncture at back-shu and front-mu acupoints in the treatment of de-pression patients with liver depression and spleen deficiency syndrome.Methods:A total of 100 patients diagnosed with depression with liver depression and spleen deficiency syndrome treated at the Second Affiliated People's Hospital of Fujian University of Tra-ditional Chinese Medicine from January 2022 to December 2022 were enrolled and randomly divided into control group and observa-tion group,with 50 cases in each group.The control group was treated with oral administration of escitalopram for one month,while the observation group were treated with acupuncture at back-shu and front-mu acupoints based on the control group,with treatment administered once every 2 days for a total of 15 times.The main symptoms,depression severity,quality of life scores,serum 5-hydroxytryptamine(5-HT)levels,intestinal flora,adverse reactions,recurrence rate,and clinical efficacy were compared before and after treatment between the two groups.Results:After treatment,the observation group had higher scores in the Short Form Health Survey(SF-36),serum 5-HT levels,and quantities of Lactobacillus and Bifidobacterium in fecal specimens than the control group(all P＜0.05),while the scores of main symptoms,Hamilton Depression Rating Scale(HAMD-24),and quantities of Escherichia coli and Enterococcus in fecal specimens were lower than those in the control group(all P＜0.05).There was no statistically signif-icant difference in the incidence of adverse reactions between the two groups(P＞0.05).The recurrence rate in the observation group at 6 months after treatment was slightly lower than that in the control group,but the difference was not statistically significant(P＞0.05).The total effective rate in the observation group after treatment was higher than that in the control group(P＜0.05).Conclusion:Acupuncture at back-shu and front-mu acupoints has definite efficacy in the treatment of depression patients with liver depression and spleen deficiency syndrome,effectively improving symptoms,reducing depression severity,enhancing quality of life,regulating serum 5-HT levels,and improving intestinal flora distribution,with high safety.
DepressionLiver depression and spleen deficiency syndromeIntestinal floraAcupunctureBack-shu and front-mu acupointsCurative efficacy5-hydroxytryptamineQuality of life
万方数据
维普
