Bletilla striata(Thunb.)Reichb.f.is a traditional Chinese medicine which has the effects of hemostasis,anti-swelling,and promoting tissue regeneration,and is commonly used to treat traumatic bleeding,sores and swellings.Ancient records and mod-ern clinical observations have found that B.striata has the effect of treating chronic refractory wounds.Aiming to investigate the ac-tive substance basis,pharmacological effects and mechanism of B.striata in the treatment of chronic refractory wounds in the pres-ent articles,the authors reviewed the recent reports on B.striata in China and at abroad.In the process of wound repair,B.striata exhibits pharmacological effects such as hemostasis,anti-inflammation,anti-microbial,antioxidant,immune modulation,promotion of epidermal growth factor proliferation,and collagen secretion.These effects contribute to promoting the healing of chronic refractory wounds by regulating the wound micro-environment The review also discusses the challenges and solutions in the clinical applica-tion of B.striata and looks forward to its prospects in the repair of chronic wounds,providing a theoretical basis for the rational de-velopment and utilization of B.striata resources for clinical wound care.
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