As one of the main chronic complications of diabetes mellitus(DM),diabetes osteoporosis(DOP)has a hidden onset and a complex pathogenesis.It is related to the comprehensive effect of multiple factors such as hyperglycemia,oxidative stress,re-lated cytokines,hormone level changes,and the use of hypoglycemic drugs.The disease is lingering and difficult to heal,which seri-ously affects the quality of life of patients.Traditional Chinese medicine(TCM)believes that DOP is located in the bone and is closely related to dysfunction of the kidneys,spleen,liver,and organs,leading to Qi deficiency and blood stasis.Treatment often fo-cuses on regulating and tonifying the organs,promoting Qi and resolving blood stasis,and enabling the bone to nourish and improve symptoms.Based on the theory of collateral diseases,this paper studied the main pathogenesis of DOP,which was the deficiency of bone collaterals and organs,as well as the obstruction of evil blood stasis and discussed the application of the method of supplemen-ting deficiency and dredging collaterals in the prevention and treatment of DOP,so as to provide more ideas and theoretical refer-ences for clinical prevention and treatment of DOP.
关键词
糖尿病/骨质疏松症/络病理论/络虚通补法/中医/微循环/络脉/骨络
Key words
Diabetes mellitus/Osteoporosis/Collateral disease theory/Method of supplementing deficiency and dredging collater-als/Traditional Chinese medicine/Microvascular/Collateral/Bone collaterals