TCM Constitution Distribution and Clinical Characteristics of Patients with Drug-induced Liver Diseases
Objective:To analyze the distribution of sex,age,TCM constitutions,and TCM syndromes of the patients with drug-in-duced liver diseases.Methods:A total of 368 patients with drug-induced liver diseases treated in the TCM Department of Hepatolo-gy of the Fifth Medical Center of Chinese PLA General Hospital from August 2020 to August 2022 were enrolled in this study.The clinical data of the patients were collected,and the distribution and clinical characteristics of sex,age,TCM constitutions,and TCM syndromes were analyzed.Results:Qi stagnation(19.02％)was the most common TCM constitution in the patients with drug-in-duced liver diseases,followed by yin deficiency(18.21％),dampness-heat(15.22％),yang deficiency(13.32％),blood stasis(11.14％),neutral(7.61％),phlegm-dampness(6.25％),qi deficiency(5.16％),and special(4.08％).The TCM constitution distribution of the patients with drug-induced liver diseases varied regarding sex and age.Specifically,male patients mainly presen-ted the TCM constitutions of dampness-heat and yin deficiency,and female patients mainly presented the constitutions of qi stagna-tion and yin deficiency.Yin deficiency was the common constitution in both male and female patients.Qi stagnation and dampness-heat were common constitutions in the young patients,and phlegm dampness and blood stasis were common in middle-aged and old patients,respectively.In the distribution of TCM syndromes,internal accumulation of dampness-heat showed the highest frequency(125,34％),followed by liver depression and spleen deficiency(98,27％),liver-kidney yin deficiency(56,15％),qi stagnation and blood stasis(46,12％),and cold-dampness stagnation(43,12％).There was a correlation between TCM constitutions and syn-dromes in the patients with drug-induced liver diseases,and the constitution determined the susceptibility of the disease syndrome.Conclusion:According to the TCM constitutions and syndromes as well as the clinical characteristics of the patients with drug-in-duced liver diseases,the methods of regulating emotions and diets and prevention with drugs can be taken to prevent the occurrence and delay the progression of the diseases based on the differentiation of TCM constitutions,syndromes,and diseases.
Drug-induced liver diseaseDistribution of physical constitutionsClinical characteristicsTCM constitutionTCM syndromePrevention before disease onsetControlling development of existing diseaseDifferentiation of TCM constitutions,syn-dromes,and disease
万方数据
维普
