首页|基于肠道菌群探讨中医治疗多囊卵巢综合征

基于肠道菌群探讨中医治疗多囊卵巢综合征

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多囊卵巢综合征(PCOS)是一种生殖内分泌紊乱和代谢异常的疾病,常见于育龄期女性.近年研究表明PCOS可表现为不同程度的肠道菌群异常.肠道菌群参与了 PCOS的高雄激素血症、卵泡发育异常、胰岛素抵抗、肥胖和生殖内分泌异常等多个环节.基于肠道菌群的PCOS干预主要体现在饮食、运动等生活方式以及益生菌对肠道菌群的调节作用,中医药包括中草药、针灸以及其他中医特色疗法,可通过干预肠道菌群治疗PCOS.本综述为下一步PCOS肠道菌群临床研究和临床治疗PCOS提供了参考依据.
TCM Treatment of Polycystic Ovary Syndrome Based on Gut Microbiota
Polycystic ovary syndrome(PCOS)is a reproductive endocrine disorder and metabolic abnormality common in women of childbearing age.Studies have shown that PCOS is associated with varying degrees of abnormalities in gut microbiota.Gut microbio-ta has been implicated in several aspects of PCOS,including hyperandrogenemia,abnormal follicular development,insulin resist-ance,obesity,and reproductive endocrine abnormalities.Intervention measures for PCOS based on gut microbiota mainly include ad-justment in the diet,exercise,and other lifestyle,as well as the application of probiotics in the regulation of gut microbiota.Chinese medical therapies including Chinese herbal medicines,acupuncture and moxibustion,and other characteristic therapies can treat P-COS by intervening in gut microbiota.This review provides a reference for the clinical research on gut microbiota in PCOS and the clinical treatment of this disease.

Polycystic ovary syndromeGut microbiotaPathogenesisHyperandrogenismTCMChinese medicineAcupunc-tureTherapy

张婉玉、张燕丽、付新、万天恩、刘理凤、马呈呈、韩延华、吴效科、常惠

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黑龙江中医药大学,哈尔滨,150040

黑龙江中医药大学附属第一医院,哈尔滨,150040

多囊卵巢综合征 肠道菌群 发病机制 高雄激素血症 中医 中药 针刺 治法

国家自然科学基金青年科学基金国家自然科学基金面上项目中国博士后科学基金特别资助(站中)项目(第十四批)中国博士后科学基金面上项目黑龙江省自然科学基金优秀青年基金

82004404819737462021T1401882018M641886YQ2020H031

2024

10.3969/j.issn.1673-7202.2024.05.020

世界中医药
世界中医药学会联合会

世界中医药

CSTPCDCHSSCD北大核心
影响因子：1.266
ISSN：1673-7202
年,卷(期)：2024.19(5)
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