Real-world study(RWS)is a study that collects,processes,analyzes,and interprets real clinical medical data from mul-tiple perspectives.Because its results have inherent validity and external generalizability,it is increasingly valued in the field of ac-upuncture and moxibustion.By analyzing the suitability of RWS for acupuncture and moxibustion clinical research on Autism Spec-trum Disorder(ASD)in children,it is believed that RWS holds significant value in medical research on children with ASD.Howev-er,several potential problems in conducting RWS on acupuncture and moxibustion for children with ASD were identified:1)Lack of high-quality acupuncture and moxibustion clinical research evidence;2)Absence of a clinical evaluation system;3)Disconnect between clinical research outcomes and translation.In response to these problems,potential solutions for conducting RWS on acu-puncture and moxibustion for children with ASD were discussed:l)Research scenarios,study duration,and sample size should be determined based on real data;2)Due to broad inclusion and exclusion criteria,subjects had broad representativeness,and close monitoring of compliance was unnecessary;3)Non-randomized interventions should be conducted based on the child's condition and parental preferences,with longer follow-up periods to observe individualized treatment outcomes;4)RWS results should be an-alyzed reasonably from aspects such as baseline comparability,primary outcome indicators,and subgroup analysis;5)Ethically,in-formed consent methods should be selected cautiously,risk-benefit considerations and privacy protection should be rigorously re-viewed to better safeguard child ASD participants.Additionally,the future prospects of conducting RWS on acupuncture and moxi-bustion for children with ASD in real medical environments were outlined.
关键词
针灸/真实世界研究/儿童孤独症/研究方法/成果转化/疗效评价/效应优势/综述
Key words
Acupuncture and moxibustion/Real-world study/Childhood autism/Research methods/Achievement transformation/Efficacy evaluation/Effect advantage/Review
维普
万方数据