从"五脏痹"理论探析抗中性粒细胞胞质抗体相关性血管炎的病机及治疗

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国家科技期刊平台
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中文摘要：抗中性粒细胞胞质抗体(ANCA)相关性血管炎在临床上较为少见,其症状常随损伤部位不同而表现各异,本病多累及肺、肾、消化、心血管等系统,其表现同中医"五脏痹"证候相似.本文以ANCA相关性血管炎的多脏器受累与中医"五脏痹"症候的相关性为基,根据各脏临床表现不同分别从"肺痹、肾痹、脾痹、肝痹、心痹"论治,体现了中医"以五脏为中心"的理论特点,并为ANCA相关性血管炎的中医诊疗提供新的辨证思路和诊疗依据.

外文标题：Pathogenesis and Treatment of Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis from the Theory of Five Zang-organ Impediments

外文摘要：Anti-neutrophil cytoplasmic antibody(ANCA)-associated vasculitis is rare in clinical practice,with the symptoms var-ying with different disease sites.This disease involves the lung,the kidney,and the digestive,cardiovascular and other systems,with the manifestations similar to the syndrome of five zang-organ impediments in TCM.Based on the correlations between the multi-or-gan involvement of ANCA-associated vasculitis and the syndromes of five zang-organ impediments,this paper expounds the treat-ment of ANCA-associated vasculitis according to the different clinical manifestations of lung impediment,kidney impediment,spleen impediment,liver impediment,and heart impediment.This treatment principle reflects the theoretical characteristic of TCM focusing on the five zang-organs and provides new ideas for the syndrome differentiation and treatment in the management of ANCA-associat-ed vasculitis.

外文关键词：

Five zang-organ impedimentsAnti-neutrophil cytoplasmic antibody-associated vasculitisHolistic viewSyndrome differentiation and treatmentEtiology and pathogenesisSyndrome

作者：

卢姝妍、李桓、杜萌萌、周全

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作者单位：

河南中医药大学,郑州,450046

河南中医药大学第一附属医院,郑州,450099

关键词：

五脏痹抗中性粒细胞胞质抗体相关性血管炎整体观辨证论治病因病机证候

基金：

2022年中国博士后科学基金第71批面上项目河南省中医药科学研究专项河南省中医药科学研究专项

项目编号：

2022M7110832021JDZX20132022JDZX112

出版年：

2024

DOI：

10.3969/j.issn.1673-7202.2024.08.013

世界中医药

世界中医药学会联合会

世界中医药

CSTPCDCHSSCD北大核心

影响因子：1.266

ISSN：1673-7202

年,卷(期)：2024.19(8)