从"五脏痹"理论探析抗中性粒细胞胞质抗体相关性血管炎的病机及治疗
Pathogenesis and Treatment of Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis from the Theory of Five Zang-organ Impediments
卢姝妍 1李桓 2杜萌萌 2周全2
作者信息
- 1. 河南中医药大学,郑州,450046
- 2. 河南中医药大学第一附属医院,郑州,450099
- 折叠
摘要
抗中性粒细胞胞质抗体(ANCA)相关性血管炎在临床上较为少见,其症状常随损伤部位不同而表现各异,本病多累及肺、肾、消化、心血管等系统,其表现同中医"五脏痹"证候相似.本文以ANCA相关性血管炎的多脏器受累与中医"五脏痹"症候的相关性为基,根据各脏临床表现不同分别从"肺痹、肾痹、脾痹、肝痹、心痹"论治,体现了中医"以五脏为中心"的理论特点,并为ANCA相关性血管炎的中医诊疗提供新的辨证思路和诊疗依据.
Abstract
Anti-neutrophil cytoplasmic antibody(ANCA)-associated vasculitis is rare in clinical practice,with the symptoms var-ying with different disease sites.This disease involves the lung,the kidney,and the digestive,cardiovascular and other systems,with the manifestations similar to the syndrome of five zang-organ impediments in TCM.Based on the correlations between the multi-or-gan involvement of ANCA-associated vasculitis and the syndromes of five zang-organ impediments,this paper expounds the treat-ment of ANCA-associated vasculitis according to the different clinical manifestations of lung impediment,kidney impediment,spleen impediment,liver impediment,and heart impediment.This treatment principle reflects the theoretical characteristic of TCM focusing on the five zang-organs and provides new ideas for the syndrome differentiation and treatment in the management of ANCA-associat-ed vasculitis.
关键词
五脏痹/抗中性粒细胞胞质抗体相关性血管炎/整体观/辨证论治/病因病机/证候Key words
Five zang-organ impediments/Anti-neutrophil cytoplasmic antibody-associated vasculitis/Holistic view/Syndrome differentiation and treatment/Etiology and pathogenesis/Syndrome引用本文复制引用
基金项目
2022年中国博士后科学基金第71批面上项目(2022M711083)
河南省中医药科学研究专项(2021JDZX2013)
河南省中医药科学研究专项(2022JDZX112)
出版年
2024
国家科技期刊平台
NSTL
万方数据