首页|脊髓损伤"气滞血瘀"病机理论与铁死亡的关系

脊髓损伤"气滞血瘀"病机理论与铁死亡的关系

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"气滞血瘀"是脊髓损伤重要的中医病机理论,其科学内涵有待进一步阐释.铁死亡作为脊髓损伤重要的病理,其分子生物学和病理学或许与"气滞血瘀"病机理论有密切相关性.从铁死亡的调控机制入手,揭示活血化瘀中药治疗脊髓损伤的分子机制,为中医药治疗脊髓损伤提供分子生物学依据,丰富中医药现代化的研究思路和手段.
Relationship of the Pathogenesis Theory of Qi Stagnation and Blood Stasis with Ferroptosis in Spinal Cord Injury
Qi stagnation and blood stasis is a major TCM pathogenesis theory of spinal cord injury,and its scientific connotation re-mains to be explained.Ferroptosis is a key pathological mechanism of spinal cord injury,and its molecular biological basis and pathological process may be closely related to the pathogenesis theory of qi stagnation and blood stasis.Considering the regulatory mechanism of ferroptosis,this paper introduces the molecular mechanism of blood-activating and stasis-resolving Chinese medicines in treating spinal cord injury,aiming to provide molecular evidence for the TCM treatment of spinal cord injury and enrich the re-search ideas and means for the modernization of TCM.

Spinal cord injuryQi stagnation and blood stasisSyndromeBlood stasisBiological basisPathophysiologyFer-roptosis

范筱、徐立柱、陶经纬、劳克诚、戴世友、穆晓红

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青岛市市立医院,青岛,266011

北京中医药大学东直门医院,北京,100700

脊髓损伤 气滞血瘀 证候 瘀血 生物学基础 病理生理 铁死亡

国家自然科学基金项目中国博士后基金项目

822051492022M710472

2024

世界中医药
世界中医药学会联合会

世界中医药

CSTPCDCHSSCD北大核心
影响因子:1.266
ISSN:1673-7202
年,卷(期):2024.19(8)