Research Progress in the Etiology,Pathogenesis,and Treatment of Cancerous Fever
According to the available studies of both TCM and Western medicine,cancerous fever is a non-infectious fever caused by pathological factors released by the tumor tissue during the occurrence,development,and treatment of malignant tumors.The evo-lution of the condition is related to the growth and decline of the tumor,and cancer control is the key to treatment.The TCM patho-genesis of cancerous fever is characterized by stagnation,deficiency,toxin,stasis,or their combinations.The patients with stagnation mainly present qi stagnation or dampness stagnation.The former is treated by regulating liver qi,clearing heat,and purging fire,and the latter by clearing heat and draining dampness,relaxing bowels and discharging turbidity or invigorating spleen and elevating yang,resolving turbidity and removing dampness according to excess or deficient syndromes.The patients with deficiency mainly present qi deficiency,yin deficiency,or both qi and yin deficiency.In the treatment of these patients,sweet and warm medicines can be used to eliminate heat,and methods such as nourishing yin,clearing heat,and replenishing qi,can be adopted.The deficiency of healthy qi leads to the generation of cancer toxin,which consumes healthy qi,causing dampness and stasis to form phlegm and solid mass.The dysfunction of zang-fu organs leads to the formation of phlegm and toxin through steaming.The internal accumulation of toxin and pathogen consumes qi,blood,and body fluid.Toxin is not only a pathogenic factor but also a pathological product.The toxic side effects induced by surgery,chemotherapy,radiotherapy,targeted therapy,and immunotherapy,combined with the external pathogen and cancer toxin,exacerbate the accumulation of toxin,consuming healthy qi and damaging essence and blood.According-ly,the treatment should aim to clear heat,remove toxin,reinforce healthy qi,and eliminate pathogen.Stasis is caused by deficiency or excess.In the case of excess,qi and blood stasis stagnate in the meridians and transform into heat,which should be treated by ac-tivating blood,eliminating stasis,and clearing heat.In the case of deficiency,the yin and blood deficiency causes stasis in meridi-ans,which should be treated by nourishing yin,resolving stasis,and reducing fever.Based on the differentiation of pathogenesis and symptoms,acupuncture,acupoint application of Chinese medicines and other therapies can be used.After the heat is under control,attention should be paid to the cancer to prevent recurrence.
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