Effect of Xinnaoning Capsules on Patients with Angina Pectoris after Percutaneous Coronary Intervention
Objective:To investigate the effect of Xinnaoning Capsules on angina pectoris in patients with coronary heart disease(CHD)after percutaneous coronary intervention(PCI).Methods:A total of 132 CHD patients with varying degrees of angina pec-toris after PCI,admitted to the Department of Cardiovascular Medicine at Hebei Provincial Hospital of Traditional Chinese Medicine between May 2021 and March 2022,were enrolled and divided into a control group and an observation group by simple randomiza-tion(coin tossing),with 66 patients in each group.Both groups received conventional western medicine treatment.The control group was given a placebo,while the observation group received Xinnaoning Capsules orally.The incidence of angina attacks,the reduc-tion and discontinuation rate of nitroglycerin,blood lipid levels,plaque area,Seattle Angina Questionnaire scores,and adverse reac-tions were compared before and after treatment between the two groups.Results:After 24 weeks of treatment,both groups showed significant improvement in the incidence of angina attacks,nitroglycerin reduction and discontinuation rates,triglycerides,total cho-lesterol,and low-density lipoprotein cholesterol levels compared to the conditions before treatment,with the observation group show-ing more significant improvement(all P＜0.05).After treatment,both groups also showed improvements in physical activity limita-tions,stability of angina,incidence of angina attacks,treatment satisfaction,and disease awareness(all P＜0.05).Conclusion:Xin-naoning Capsules combined with western medicine in the short-term treatment of angina pectoris in CHD patients after PCI can re-duce the frequency and duration of angina attacks,decrease the use of anti-angina medications,and effectively control blood lipid levels,with few adverse reactions.
Xinnaoning CapsulesPercutaneous coronary interventionPostoperativeAtherosclerosisAngina pectorisBlood lipidsSyndrome of qi stagnation and blood stasisSeattle Angina QuestionnaireAdverse reactions
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