Understanding of Constipation-predominant Irritable Bowel Syndrome with Anxiety and Depression Based on Brain-gut Axis Theory from Traditional Chinese and Western Medicine Perspectives
With the research and advancements in Western medicine,most medical experts believe that there is a clear link be-tween the psychological state and constipation-predominant irritable bowel syndrome(IBS-C).The brain-gut axis plays a crucial role in the pathogenesis of both conditions,and the use of brain-gut interaction theory for treating this disease has received wide-spread attention.According to Western medicine,factors such as brain-gut peptides and imbalances in gut microbiota can lead to symptoms of IBS-C,including abdominal pain and changes in mental and psychological state.Traditional Chinese medicine(TCM)often associates the brain-gut axis theory with different TCM syndrome types.This article reviewed the pathogenesis of IBS-C with anxiety and depression from the perspective of the brain-gut axis,focusing on brain-gut peptides,gut microbiota,hypothalamic-pitui-tary-adrenal(HPA)axis,psychological factors,and TCM treatment,so as to offer new insights to clinicians for the diagnosis and treatment of this condition.
国家科技期刊平台
NSTL
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