摘要
桂枝附子汤出自《伤寒论》和《金匮要略》原文,桂枝附子汤证的核心病机是风湿搏结、正虚邪壅,其主要临床症状为身体烦疼、活动障碍,而祛风散寒、除湿止痛是桂枝附子汤的主要治疗方义.桂枝附子汤具祛风除湿、温阳散寒、通痹止痛之效,是中医治疗痹病的经典方剂,现代临床广泛应用于类风湿关节炎、痛风性关节炎、坐骨神经痛、肩周炎、神经根型颈椎病等疾病的治疗,疗效确切.桂枝附子汤的现代药理学作用机制可能与抗炎镇痛、调节免疫、改善关节症状等密切相关.
Abstract
Guizhi Fuzi Decoction,derived from Treatise on Cold Damage(Shang Han Lun)and Synopsis of the Golden Chamber(Jin Gui Yao Lue),addresses the syndromes with core pathogenesis of wind-dampness obstruction and healthy qi deficiency with pathogen retention.The main indicated clinical symptoms include generalized pain and restricted movement.The primary therapeu-tic principles of Guizhi Fuzi Decoction are to dispel wind,dissipate cold,eliminate dampness,and relieve pain.Guizhi Fuzi Decoc-tion,known for its effects of expelling wind,eliminating dampness,warming yang,dissipating cold,and unblocking obstructions to alleviate pain,is a classic prescription in traditional Chinese medicine(TCM)for treating impediment diseases.In modern clinical practice,Guizhi Fuzi Decoction is widely used to treat conditions such as rheumatoid arthritis,gouty arthritis,sciatica,frozen shoul-der,and radicular cervical spondylosis,with definite efficacy.The pharmacological mechanisms underlying the therapeutic effects of Guizhi Fuzi Decoction may be closely related to its anti-inflammatory and analgesic properties,immune regulation,and improvement of joint symptoms.
基金项目
国家自然科学基金项目(82074563)
中国中医科学院科技创新工程项目(CI2021A00104)
中国中医科学院中医基础理论研究所自主选题项目(YZX-202247)
维普
万方数据