Randomized Controlled Study on the Treatment of Metabolic Syndrome with Lu's Spleen-invigorating and Stomach-harmonizing Acupuncture Method
Objective:To observe the clinical efficacy of Lu's spleen-invigorating and stomach-harmonizing acupuncture method in the treatment of metabolic syndrome(MetS).Methods:Ninety MetS patients who visited the Seventh People's Hospital of Shanghai from March 2020 to March 2022 were enrolled and randomly divided into an observation group and a control group according to a random number table,with 45 patients in each group.The control group received health education and conventional drug treatment,while the observation group additionally received Lu's spleen-invigorating and stomach-harmonizing acupuncture method.Changes in weight,waist circumference,body mass index(BMI),blood lipids,blood glucose,and blood pressure were compared before and after treatment in both groups.Results:Intent-to-treat(ITT)analysis showed that weight,waist circumference,and BMI significantly decreased at each time point in both groups compared to those before treatment(P＜0.05).The weight,waist circumference,and BMI in the observation group were lower than those in the control group at each time point(P＜0.05).After treatment,both groups showed significant decreases in serum total cholesterol(TC)and low-density lipoprotein cholesterol(LDL-C)(P＜0.05),and sig-nificant increases in high-density lipoprotein cholesterol(HDL-C)compared to those before treatment(P＜0.05).The changes in TC,triglycerides(TG),and HDL-C were more significant in the observation group than in the control group(P＜0.05).Fasting blood glucose(FBG),glycated hemoglobin(HbAlc),and homeostasis model assessment of insulin resistance(HOMA-IR)de-creased significantly in both groups after treatment(P＜0.05),with greater reductions in the observation group than in the control group(P＜0.05).There were no significant changes in blood pressure indicators before and after treatment in either group(P＞0.05),and the expectation of acupuncture efficacy was not significantly correlated with clinical outcomes(P＞0.05).Conclusion:Lu's spleen-invigorating and stomach-harmonizing acupuncture method can effectively reduce weight,waist circumference,and BMI in MetS patients,improve blood lipid and blood glucose levels,and has good long-term efficacy.
AcupunctureMetabolic syndromeLu's acupuncture and moxibustionSchool inheritanceRandomized controlled trialMeridian and collateralsSyndrome differentiationInvigorating the spleen and harmonizing the stomachLong termEfficacy
万方数据
维普
