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中医药治疗男性不育症临床研究与展望

A Review and Prospect of Clinical Research on the Treatment of Male Infertility with Traditional Chinese Medicine

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近年来,中医学者对男性不育症理论基础的不断深入研究,使男性不育症患者有望获得更为安全有效的治疗手段.随着时代的发展,中医药治疗男性不育症与时俱进,出现新思维,考虑多病机、多脏腑论治,从以往的单用补肾之法到现在的疏肝解郁、清利湿热、活血化瘀之法并用.肾虚虽是导致男性不育的最关键的病因病机,但七情、湿、热、痰、瘀、虫、毒等病理因素的影响同样不可忽视.该病辨证论治时,需注意个人特质,辨病、辨证论治相结合,以更好发挥中医药治疗之优势.中医药治疗男性不育症不仅可改善精液指标、缓解其伴随症状,还可减少可能发生的不良反应.中西医融合治疗男性不育症,优势互补,相辅相成,中医药可用于治疗西医发病机制不明确的特发性少弱精子症,并使得西医辅助生殖术后出现并发症的概率降低,提高妊娠率.但今后中医药治疗男性不育症仍需要重视理论创新,并开展高层次的临床研究,从而推动制定标准的中医药治疗男性不育症的诊疗方案,促进其临床的推广与应用.
In recent years,the deepening research by traditional Chinese medicine(TCM)scholars on the theoretical foundations of male infertility has provided hope for patients to access safer and more effective treatment methods.As times have evolved,TCM approaches to treating male infertility have also advanced,introducing new perspectives.These approaches consider syndrome differ-entiation based on multiple pathogenic mechanisms and multiple organs,moving from the traditional sole focus on tonifying kidney to incorporating methods such as soothing the liver and relieving depression,clearing dampness-heat,and promoting blood circula-tion to remove stasis.While kidney deficiency remains the most critical pathogenic cause of male infertility,the impact of pathologi-cal factors such as emotional disturbances,dampness,heat,phlegm,blood stasis,parasites,and toxins should not be overlooked.In syndrome differentiation and treatment,it is important to consider individual characteristics,combining disease differentiation with syndrome differentiation to better leverage the advantages of TCM.TCM treatment of male infertility not only improves semen pa-rameters and alleviates accompanying symptoms but also reduces the likelihood of adverse reactions.The integration of TCM and Western medicine in treating male infertility provides complementary advantages,with TCM being particularly effective in treating idiopathic oligoasthenospermia,where the pathogenic mechanisms are unclear in Western medicine.It can also reduce the incidence of complications following assisted reproductive techniques in Western medicine and improve pregnancy rates.However,moving for-ward,TCM treatment of male infertility must continue to emphasize theoretical innovation and conduct high-level clinical research.It will drive the development of standardized TCM treatment protocols for male infertility,promoting its clinical application and widespread adoption.

Male infertilityTraditional Chinese medicineClinical researchTreatmentReviewDominanceProspect

冯隽龙、厉将斌、孙松、高子翔、王彬、王继升、赵聪、李海松

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北京中医药大学东直门医院,北京,100700

北京市昌平区中医医院,北京,102200

男性不育症 中医药 临床研究 治疗 述评 优势 展望

国家自然科学基金面上项目中华中医药学会青年求实项目

821743852021-QNQS-03

2024

世界中医药
世界中医药学会联合会

世界中医药

CSTPCDCHSSCD北大核心
影响因子:1.266
ISSN:1673-7202
年,卷(期):2024.19(16)