Endometriosis(EMT)is a chronic estrogen-dependent disease,with dysmenorrhea being its most characteristic clinical symptom.The incidence of EMT has been rising annually in recent years,significantly affecting women's quality of life.Traditional Chinese medicine(TCM)posits that"stagnation leading to pain",identifying this as a primary mechanism for dysmenorrhea associ-ated with EMT.Modern medicine has discovered that the occurrence of EMT is linked to processes such as angiogenesis,epithelial-mesenchymal transition,and immune inflammation.Recent literature indicates that TCM can improve dysmenorrhea associated with EMT by regulating autophagy,exerting immunomodulatory and anti-inflammatory effects,inhibiting uterine smooth muscle contrac-tions,improving uterine blood rheology,reducing pain sensitivity,and suppressing the implantation,adhesion,and invasion of ectop-ic tissues.Guided by TCM theory and starting from the integration of TCM and Western medicine,this research summarized the mechanisms of TCM in treating dysmenorrhea in EMT in modern medical theory to explore new ideas and methods for TCM in ad-dressing dysmenorrhea associated with EMT.
关键词
子宫内膜异位症/痛经/中医药/瘀血阻滞/不通则痛/辨证论治/作用机制
Key words
Endometriosis/Dysmenorrhea/Traditional Chinese medicine/Blood stasis obstruction/Stagnation leading to pain/Treatment based on syndrome differentiation/Mechanism of action