首页|基于"肺与大肠互为表里"探析肺肠传变

基于"肺与大肠互为表里"探析肺肠传变

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肺与大肠是互为表里的2个脏腑,中医学将二者的关系概括为经脉相互络属、生理病理相互关联.经梳理文献发现肺与大肠在胚胎起源、神经体液调节、免疫学、信号通路转导、肠道菌群系统等方面均具有密切的联系,这种生理病理的关系是肺与大肠互为表里的基础.在此基础上根据肺肠之间肺病及肠、肠病及肺的传变关系,采用肺病治肠、肠病治肺以及肺肠合治的治疗方案,结合流行病学和循证医学,可将肺与大肠互为表里的理论进一步深化和应用.
Pulmonary Intestinal Transmission Based on the Theory of"Interior-exterior Relationship between Liver and Gallbladder"
The lung and large intestine are paired organs with interior-exterior relationship,and in traditional Chinese medicine(TCM),their relationship is summarized as being interconnected through meridians and collaterals and sharing physiological and pathological associations.A review of the literature reveals that the lung and large intestine are closely linked in embryonic origin,neurohumoral regulation,immunology,signal transduction pathways,and gut microbiota systems.These physiological and pathologi-cal interconnections form the basis of interior-exterior relationship of the lung and large intestine.Building on this foundation,the transmission dynamics between pulmonary diseases affecting the intestine and intestinal diseases affecting the lung have led to ther-apeutic strategies such as treating intestinal diseases to address lung disorders,treating lung diseases to manage intestinal condi-tions,or adopting combined lung-intestine treatments.By integrating epidemiological findings and evidence-based medicine,the the-oretical framework of the lung and large intestine as paired organs can be further refined and applied in clinical practice.

LungLarge intestinePhysiology and pathologyTraditional Chinese medicineEpidemiologyMeridianImmunolo-gySignaling pathwayGut microbiota

周鹏飞、陆金根、姚一博、孙琰婷、张胜威、唐勇、郭思清、王佳雯

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上海中医药大学附属龙华医院,上海,200030

上海中医药大学,上海,200000

河南中医药大学第五临床医学院/郑州人民医院,郑州,450000

江西中医药大学附属医院,南昌,330000

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大肠 生理病理 中医学 流行病学 经脉 免疫学 信号通路 肠道菌群

2024

世界中医药
世界中医药学会联合会

世界中医药

CSTPCDCHSSCD北大核心
影响因子:1.266
ISSN:1673-7202
年,卷(期):2024.19(19)