Therapeutic Value of Wenjing Zhitong Decoction Combined with Tuina on Primary Dysmenorrhea Patients
Objective;To investigate the therapeutic value of Wenjing Zhitong Decoction combined with tuina in the treatment of primary dysmenorrhea.Methods:A total of 150 patients with primary dysmenorrhea who were admitted to Dongfang Hospital of Bei-jing University of Chinese Medicine from January 2020 to March 2023 were selected for this study.The patients were randomly di-vided into a control group and an observation group according to a random number table,with 75 cases in each group.The control group received tuina therapy,while the observation group received both tuina therapy and Wenjing Zhitong Decoction.The clinical efficacy of the two groups was compared,as well as the assessment of traditional Chinese medicine(TCM)syndrome scores,visual analog scale(VAS)scores,and levels of prostaglandin F2α(PGF2α),prostaglandin E2(PGE2),beta-endorphin(β-EP),substance P(SP),dopamine(DA),serotonin(5-HT).Additionally,uterine artery blood flow pulsatility index(PI),resistance index(RI),and systolic/diastolic peak ratio(S/D)were measured.Results:The total effective rate in the observation group was significantly higher than in the control group(P＜0.05).The observation group had lower TCM syndrome scores after treatment than the control group(P＜0.05).The VAS score in the observation group was(1.21±0.15),significantly lower than(2.03±0.56)of the control group(t=12.249,P=0.000).After treatment,serum levels of PGF2α,SP,DA,and 5-HT were lower in the observation group than in the control group,while serum levels of PGE2 and β-EP were higher.Furthermore,the observation group showed significantly low-er PI,RI,and S/D values than the control group(P＜0.05).Conclusion:Wenjing Zhitong Decoction combined with tuina therapy effectively alleviates clinical symptoms,signs,and pain in patients with primary dysmenorrhea,and also improves serum levels of PGF2α,pain-related factors,and uterine artery hemodynamic indicators.
万方数据
维普
