世界中医药2024,Vol.19Issue(19) :3015-3022.DOI:10.3969/j.issn.1673-7202.2024.19.021

基于"脏腑-骨痿"理论探讨绝经后骨质疏松症的发病机制

Pathogenesis of Postmenopausal Osteoporosis Based on"Internal Organ-bone Flaccidity"Theory

黎征鹏 章晓云 曾浩 高振罡
世界中医药2024,Vol.19Issue(19) :3015-3022.DOI:10.3969/j.issn.1673-7202.2024.19.021

基于"脏腑-骨痿"理论探讨绝经后骨质疏松症的发病机制

Pathogenesis of Postmenopausal Osteoporosis Based on"Internal Organ-bone Flaccidity"Theory

黎征鹏 1章晓云 2曾浩 1高振罡1
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作者信息

  • 1. 广西中医药大学研究生学院,南宁,530000
  • 2. 广西中医药大学研究生学院,南宁,530000;广西中医药大学附属瑞康医院,南宁,530011
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摘要

绝经后骨质疏松症(PMOP)是一种常见的骨骼疾病,属于高转换型的骨质疏松症(OP),好发于女性绝经后5~10年.由于绝经后女性卵巢衰退,雌性激素和相关激素水平紊乱,进而引起骨量减少和骨微观结构发生改变,骨脆弱增加,患者骨折风险增加.中医学认为,肾虚是本病发生的关键,肾精充足对于骨髓充养和骨密度的提高起着至关重要的作用.同时,肝主疏泄,脾主运化,肺主行气,心血亏虚、胆气不足、肠道功能紊乱等因素同样影响骨的生长.

Abstract

Postmenopausal osteoporosis(PMOP)is a common skeletal disorder classified as high-turnover osteoporosis(OP),most prevalent in women 5 to 10 years after menopause.The condition arises from ovarian decline in postmenopausal women,leading to disruptions in estrogen and related hormone levels,which result in reduced bone mass,altered bone microarchitecture,increased bone fragility,and a heightened risk of fractures.In traditional Chinese medicine(TCM),kidney deficiency is considered a key fac-tor in the development of this condition.Adequate kidney essence plays a crucial role in nourishing bone marrow and improving bone density.Additionally,the liver's function in regulating the smooth flow of qi,the spleen's role in transportation and transforma-tion,and the lung's regulation of qi circulation are all vital.Other factors,such as heart blood deficiency,insufficient gallbladder qi,and intestinal dysfunction,also influence bone growth and health.

关键词

绝经后骨质疏松症/脏腑/中医理论/发病机制/气血/津液/气机/气机升降

Key words

Postmenopausal osteoporosis/Internal organs/Traditional Chinese medicine theory/Pathogenesis/Qi and blood/Body fluid/Qi movement/Ascending and descending of qi movement

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出版年

2024
世界中医药
世界中医药学会联合会

世界中医药

CSTPCDCHSSCD北大核心
影响因子:1.266
ISSN:1673-7202
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