世界中医药2024,Vol.19Issue(19) :3032-3038.DOI:10.3969/j.issn.1673-7202.2024.19.024

经典名方枳实薤白桂枝汤的现代研究及展望

Modern Research and Prospect of Classic Formula Zhishi Xiebai Guizhi Decoction

魏娇霞 付敏 李媛 牛征 张轩宇 姚丽
世界中医药2024,Vol.19Issue(19) :3032-3038.DOI:10.3969/j.issn.1673-7202.2024.19.024

经典名方枳实薤白桂枝汤的现代研究及展望

Modern Research and Prospect of Classic Formula Zhishi Xiebai Guizhi Decoction

魏娇霞 1付敏 1李媛 1牛征 1张轩宇 1姚丽1
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作者信息

  • 1. 哈尔滨医科大学药学院,哈尔滨,150081
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摘要

枳实薤白桂枝汤为治疗胸痹之经典名方,收录于国家中医药管理局公布的第一批《古代经典名方目录》,临床用于治疗心血管疾病、呼吸系统疾病、消化系统疾病等,对冠心病疗效尤为显著,是开发治疗心血管疾病创新药物的重要来源.但其有效成分不明、作用机制不清成为其现代研发的瓶颈.通过整合梳理近30年枳实薤白桂枝汤研究进展,全面分析其活性成分,系统总结其药理作用机制,以期为经典名方枳实薤白桂枝汤的临床应用和药物研发提供有益参考.

Abstract

Zhishi Xiebai Guizhi Decoction,a classic formula for the treatment of chest impediment syndrome,is included in the first batch of the Catalogue of Ancient Classic Prescriptions published by the National Administration of Traditional Chinese Medi-cine.Clinically,it is widely used to treat cardiovascular,respiratory,and digestive system diseases,with particularly notable efficacy in managing coronary heart disease.It serves as an important source for developing innovative drugs for cardiovascular conditions.However,unclear active components and undefined mechanisms of action have posed significant challenges to its modern develop-ment.By reviewing and integrating research advancements on Zhishi Xiebai Guizhi Decoction over the past 30 years,this study com-prehensively analyzes its active components and systematically summarizes its pharmacological mechanisms,aiming to provide valu-able insights into the clinical applications and drug development potential of Zhishi Xiebai Guizhi Decoction.

关键词

枳实薤白桂枝汤/胸痹/经典名方/活性成分/药理作用/临床应用/研究进展/药物研发

Key words

Zhishi Xiebai Guizhi Decoction/Chest impediment/Classic formula/Active components/Pharmacological effect/Clinical application/Research progress/Drug development

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出版年

2024
世界中医药
世界中医药学会联合会

世界中医药

CSTPCDCHSSCD北大核心
影响因子:1.266
ISSN:1673-7202
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