Influences of TPMS Bone Scaffold Porous Structures on the Permeability
Bone scaffolds designed based on three-period minimal surface(TPMS)have attracted much attentions in the bone tissue engineering,and the permeability is one of the main indexes for evaluating the performances of bone scaffolds.In this paper,the lamellar(L)and rod(R)type TPMS bone scaffold structures with three different types of Diamond(D),Gyroid(G)and I-WP were constructed.Poly(lactic acid)was selected as the bone scaffold material.The effects of cell size and porosity on the permeability performance of bone scaffold structures were analyzed by finite element simulations.The results show that,for the same type TPMS bone scaffold structures,the permeability of rod-shaped bone scaffold is better than that of lamellar bone scaffold under the conditions of the same unit size and porosity.The permeability of I-WP type bone scaffold is significantly higher than those of other two types,and the permeability of D type bone scaffold is higher than that of G type.The permeability of bone scaffolds with different types is affected by the cell size and porosity,and the permeability increases with the increase of cell size and porosity.Further,this paper analyzed the permeability of three rod-shaped TPMS bone scaffolds,and obtained the permeability fitting formulas of rod-shaped TPMS bone scaffolds based on the unit size and porosity,providing the theoretical guidance for the optimal designs and practical applications of TPMS bone scaffolds.
万方数据
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