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COVID-19相关心肌炎的研究进展

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严重急性呼吸综合征冠状病毒 2(severe acute respiratory syndrome coronavirus 2,SARS-CoV-2)是一种新型冠状病毒,主要感染肺脏造成新型冠状病毒肺炎(coronavirus disease 2019,COVID-19).近年的临床病例报告了其心血管系统并发症主要为心肌炎、心律失常、心肌梗死等.其中,COVID-19相关心肌炎症状多样,不同年龄段均可发生,存在延迟发作,且与COVID-19患者的不良预后和死亡率呈正相关.因此,研究其临床特点、潜在发病机制和治疗方法可对未来COV-ID-19 相关心肌炎的防治及药物开发提供新的思路和策略.本文将结合国内外关于COVID-19相关心肌炎的研究进行概述.
Research Progress on COVID-19-Related Myocarditis
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is a novel coronavirus that primarily affects the lungs and causes coronavirus disease 2019(COVID-19).Recent clinical cases have reported the cardiovascular complications of COVID-19,including myocarditis,ar-rhythmia,myocardial infarction,and so on.Among them,COVID-1 9-related myocarditis exhib-its diverse symptoms,which can occur at different ages and has a delayed onset.Moreover,CO-VID-19-related myocarditis is positively correlated with the poor prognosis and mortality of COV-ID-19 patients.The exploration of its clinical characteristics,potential pathogenesis and treat-ment may provide new ideas and strategies for the prevention and drug development of COVID-19-related myocarditis in the future.This article provides an overview of both domestic and for-eign researches on COVID-19-related myocarditis.

SARS-CoV-2myocarditismechanismtreatmentprogress

李玥霖、赵伊帆、郝丽英、胡慧媛

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中国医科大学药学院药物毒理学教研室,沈阳 110122

SARS-CoV-2 心肌炎 机制 治疗 进展

国家自然科学基金辽宁省教育厅基本科研项目中国医科大学新冠肺炎疫情防控相关科研攻关项目

81100108JYTMS202301302020-07

2024

生理科学进展
中国生理学会,北京大学

生理科学进展

CSTPCD北大核心
影响因子:0.635
ISSN:0559-7765
年,卷(期):2024.55(2)
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