摘要
昼夜节律(circadian rhythm)是一种大约以24小时为周期自然循环的生物过程,包括血压、心率和体温等在内的多种生理功能均呈现明显的昼夜节律.血压正常的昼夜节律呈现"两峰一谷"的杓型变化,且受到光线、运动、摄食等多种外源性因素及自主神经系统、应激相关激素、时钟基因等多种内源性因素的共同调节.近年来,夜间光暴露、轮班、时差等生活因素引起机体出现昼夜节律紊乱的现象逐渐增加,血压的正常昼夜节律也经常受到影响而发生昼夜节律紊乱.大量研究表明,运动可以预防高血压、心力衰竭等心血管疾病,是改善心血管疾病患者血压昼夜节律紊乱重要的非药物预防手段.因此,本文将以影响血压昼夜节律的因素为出发点,旨在阐明运动参与血压昼夜节律调节的可能机制,并为运动改善血压昼夜节律紊乱提供理论依据.
Abstract
Circadian rhythm is a biological process that operates on an approximately 24-hour cy-cle,encompassing various physiological functions including blood pressure,heart rate,and body temperature.The normal circadian rhythm of blood pressure typically exhibits a characteristic"two-peak and one-valley"pattern,which is regulated by a combination of exogenous factors,in-cluding light exposure,exercise,and diet,as well as endogenous factors such as the autonomic nervous system,stress hormones,and clock genes.In recent years,lifestyle factors such as noc-turnal light exposure,shift work,and jet lag have increasingly led to circadian rhythm disrup-tion.The normal circadian rhythm of blood pressure is also often affected,contributing to circa-dian rhythm disorders of blood pressure.Numerous studies indicate that exercise can prevent car-diovascular diseases such as hypertension and heart failure,serving as an important non-pharma-cological strategy to mitigate the disruptions in the circadian rhythm of blood pressure.There-fore,this review will take the factors influencing the circadian rhythm of blood pressure as a starting point,aiming to clarify the possible mechanisms through which exercise participates in regulating the blood pressure circadian rhythm,and to provide a theoretical basis for improving the circadian rhythm disorders of blood pressure through exercise.
维普
万方数据