数理统计与管理2024,Vol.43Issue(1) :20-31.DOI:10.13860/j.cnki.sltj.20230629-003

妊娠早期甲状腺功能减退症相关因素探讨和发病概率预测

Study on Related Factors of Hypothyroidism in Early Pregnancy and Prediction of Incidence Probability

高庆 宋泽芳 刘玉娇
数理统计与管理2024,Vol.43Issue(1) :20-31.DOI:10.13860/j.cnki.sltj.20230629-003

妊娠早期甲状腺功能减退症相关因素探讨和发病概率预测

Study on Related Factors of Hypothyroidism in Early Pregnancy and Prediction of Incidence Probability

高庆 1宋泽芳 2刘玉娇3
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作者信息

  • 1. 山东省临沂市妇幼保健院,山东临沂 276000
  • 2. 广州大学经济与统计学院,广东广州 510006;广州大学岭南统计科学研究中心,广东广州 510006
  • 3. 广州大学经济与统计学院,广东广州 510006
  • 折叠

摘要

基于2017年-2019年临沂市妇幼保健院的39001例妊娠早期孕妇的临床数据,建立不同年龄阶段的平衡化logistic回归模型,实证检验年龄、抗甲状腺过氧化物酶抗体(TPOAB)对妊娠期甲状腺功能减退症的影响.结果表明,抗甲状腺过氡化物酶抗体(TPOAB)是影响妊娠期甲状腺功能减退症的主要因素,但存在年龄差异,30岁和40岁以上的人群是高发人群.基于上述结论提出预防妊娠期甲状腺功能减退的对策建议.

Abstract

Based on the early pregnancy clinical data of pregnant women which quantity is 39,001 from Linyi Maternal and Child Health Hospital from 2017 to 2019,balanced logistic regression model at different ages was established,the model was established to test the effect of anti-thyroid peroxidase antibody(TPOAB)on hypothyroidism during pregnancy empirically.The result shows that antithyroid peroxidase antibody(TPOAB)is the main factor which is affecting hypothyroidism during pregnancy,however,the age differences are exist,People in their 30s and 40s are at high risk.Based on the above conclusions,Prevention of hypothyroidism of pregnancy were proposed.

关键词

logistic回归/妊娠期甲状腺功能减退症/年龄/抗甲状腺过氧化物酶抗体

Key words

logistic regression/hypothyroidism of pregnancy/age/thyroid peroxidase antibody

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基金项目

临沂市科技创新发展计划(医学类)基金资助项目(201919043)

国家自然科学基金(11701116)

广州市基础与应用基础研究项目(202201010276)

出版年

2024
数理统计与管理
中国现场统计研究会

数理统计与管理

CSTPCDCSSCICHSSCD北大核心
影响因子:1.114
ISSN:1002-1566
参考文献量21
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