The fact that Limnoperna fortunei adhere to the walls of water conveyance structures will lead to many se-rious problems,such as deterioration of concrete performance and an increase in roughness.However,there is still a lack of practical and effective prevention and control measures.A non-toxic,novel protective coating has been developed to address the challenges in controlling Limnoperna fortunei in water conveyance structures.The micro-structure,surface energy,and mechanical properties of the coating were characterized through experimental meth-ods.We studied the behavioral characteristics of Limnoperna fortunei on the surface of coatings,comparing the av-erage adhesion rate and average vertical separation force between the developed coating and six existing coating sur-faces.We also deeply analyzed the adhesion mechanism of it on the existing coating surface and the anti-adhesion mechanism of the developed coating.The results showed that,compared with the silicone rubber coating,which had the best anti-adhesion effect among the six non-toxic existing coatings,the coating developed in this paper ex-hibited a decrease in both the average adhesion rate and average vertical separation force of Limnoperna fortunei on the coating surface by 58.33%and 46.67%,respectively.Compared with the concrete surface,the average adhe-sion rate and average vertical separation force decreased by 80.26%and 91.11%,respectively.The developed coating has the characteristics of"low surface energy","microstructure","elasticity",and"low pollution re-moval parameters",and its pollution removal parameters are superior to similar coatings.This study can provide a reference for the selection and performance analysis of protective coatings for Limnoperna fortunei in water convey-ance structures.In addition,it provides a new path for the prevention and control of Limnoperna fortunei.