首页|山药多糖对犊牛免疫功能、抗氧化能力及肠道菌群的影响

山药多糖对犊牛免疫功能、抗氧化能力及肠道菌群的影响

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试验旨在探讨山药多糖对犊牛免疫功能、抗氧化能力及肠道菌群的影响。选择36头(30±3)d、体重(55。27±1。53)kg的健康荷斯坦犊牛,随机分为2组,每组18个重复,每个重复1头牛。对照组(CG组)饲喂代乳粉5L/(头·d),试验组(EG组)饲喂含10 g山药多糖的代乳粉5 L/(头·d)。试验期10 d。结果显示,与CG组相比,EG组犊牛血清免疫球蛋白A(IgA)、免疫球蛋白G(IgG)、免疫球蛋白M(IgM)、肿瘤坏死因子-α(TNF-α)含量及超氧化物歧化酶(SOD)活性显著升高(P<0。05)。EG组犊牛肠道菌群OTUs增多,有益菌厚壁菌门(Firmicutes)、变形菌门(Proteobacteria)、放线菌门(Actinobacteriota)的相对丰度分别提高了 21。67%、60。83%、88。25%,有害菌梭杆菌门相对丰度减少。研究表明,在犊牛代乳粉中添加山药多糖可增强犊牛免疫功能,提高抗氧化能力,能够通过增加肠道有益菌数量,减少有害菌数量,调节肠道菌群结构。
Effects of Chinese yam polysaccharides on immune function,antioxidative capacity,and intestinal microbiota in calves
The study aimed to explore the effects of Chinese yam polysaccharides on the immune function,antioxidative capacity,and intestinal microbiota of calves.Thirty-six healthy Holstein calves with an age of(30±3)days and a weight of(55.27±1.53)kg were randomly divided into two groups,with 18 replicates per group and one calf per replicate.The control group(CG group)was fed with 5 L/(head·d)of milk,while the experimental group(EG group)was fed with 5 L/(head·d)of milk containing 10 g of Chinese yam polysaccharidess.The experimental period lasted for 10 days.The results showed that compared to the CG group,the EG group exhibited a significant increase in the serum concentrations of IgA,IgG,IgM,TNF-α,and the activity of SOD(P<0.05).The EG group showed an increase in OTUs in the intestinal microbiota,with a notable elevation in the abundance of beneficial bacteria(Firmicutes,Proteobacteria,and Actinobacteriota)by 21.67%,60.83%,and 88.25%,respectively,while harmful bacteria of the phylum Bacteroidetes decreased.The study inidicates that adding Chinese yam polysaccharides to calf milk replacer can enhance immune function,improve antioxidative capacity,and regulate intestinal microbiota by increasing beneficial bacteria and reducing harmful bacteria.

Chinese yam polysaccharidescalvesantioxidative capacityimmuneintestinal microbiota

路晨月、师鑫潮、高建亭、何欣

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河北农业大学动物医学院中兽医学院,河北保定 071000

山药多糖 犊牛 抗氧化能力 免疫 肠道菌群

河北省自然科学基金河北省现代农业产业技术体系建设项目奶牛创新团队建设项目(第三期)

C2022204215HBCT2023180201

2024

饲料研究
北京市营养源研究所

饲料研究

CSTPCD北大核心
影响因子:0.391
ISSN:1002-2813
年,卷(期):2024.47(4)
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