首页|分子印迹技术在大环内酯类药物检测中的应用

分子印迹技术在大环内酯类药物检测中的应用

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  • 国家科技期刊平台
  • NETL
  • NSTL
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分子印迹技术是模拟酶-底物、抗原-抗体之间的相互作用,对印迹分子进行专一识别的技术,能够特异性识别模板或类似物,常被用于分析样品的预处理,可对样品进行高效提取和净化.大环内酯类药物是畜牧业中常用抗生素之一,广泛用于畜禽呼吸道、胃肠道感染等疾病的预防与治疗,但不规范使用可能导致其在动物产品及环境中残留,对人类健康产生威胁.文章针对分子印迹技术对大环内酯类药物残留检测的预处理技术研究进展进行综述,重点对分子印迹固相萃取和磁性分子印迹固相萃取进行介绍,并对分子印迹技术在大环内酯类药物残留分析预处理的应用前景进行展望,为优化大环内酯类抗生素检测前处理方法提供参考.
Application of molecular imprinting technology in detection of macrolides
Molecular imprinting technology is a technology that simulates the interaction between enzymes,substrates,antigens and antibodies,and specifically identifies imprinted molecules,which can specifically identify templates or analogues,and is often used in the pretreatment of analytical samples for efficient extraction and purification of samples.Macrolides are one of the commonly used antibiotics in animal husbandry,which are widely used in the prevention and treatment of respiratory tract and gastrointestinal infections in livestock and poultry,but non-standard use may lead to residues in the production of animal products and the environment,posing a threat to human health.The paper reviews the research progress of molecular imprinting technology for the detection of macrolide drug residues,focusing on the introduction of molecularly imprinted solid phase extraction and magnetic molecularly imprinted solid phase extraction,and prospects for the application of molecular imprinting technology in the pretreatment of macrolide drug residue analysis,so as to provide reference for optimizing the pretreatment method of macrolide antibiotics detection.

molecular imprinting technologymacrolide antibioticsmolecularly imprinted solid phase extractionmagnetic molecularly imprinted solid-phase extraction

王瑜、刘岑、杨智翔、段二珍、赵银丽、乔汉桢、王金荣

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河南工业大学生物工程学院,河南郑州 450001

分子印迹技术 大环内酯类抗生素 分子印迹固相萃取 磁性分子印迹固相萃取

河南工业大学青年骨干教师培育计划河南工业大学青年骨干教师培育计划

2142120821421204

2024

10.13557/j.cnki.issn1002-2813.2024.05.032

饲料研究
北京市营养源研究所

饲料研究

CSTPCD北大核心
影响因子：0.391
ISSN：1002-2813
年,卷(期)：2024.47(5)
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