Study on antioxidant activity of Codonopsis polysaccharides and their effects on serum immunity and antioxidant function in laying hens
The purpose of this study was to explore the antioxidant activity of Codonopsis polysaccharide(CPP)and its effect on serum immunity and antioxidant function of laying hens.In vitro tests were used to test the scavenging ability of CPP on DPPH free radicals,hydroxyl free radicals and ABTS+free radicals,and in vivo tests were used to examine the effects of CPP on laying hens serum Newcastle disease antibody titer and antioxidant enzyme activities.Forty one-day-old healthy Roman laying hens were randomly divided into four groups with 10 replicates per group and one laying hen per replicate.Laying hens were divided into CPP high concentration group(CPPH group),CPP low concentration group(CPPL group),immune control group(VC group)and blank control group(BC group),respectively.The experiment lasted for 35 days.The results showed that CPP had different degrees of scavenging ability against DPPH free radicals,hydroxyl radicals and ABTS+free radicals,and its antioxidant activity was significantly enhanced with the increase of CPP concentration.At 7 and 21 days after the first immunization,the serum CAT,GSH-Px activities,and Newcastle disease antibody titers in the CPPH group were significantly higher than those in the VC group and BC group(P＜0.05).The results showed that CPP had strong antioxidant activity,which could improve the serum antioxidant enzyme activities and Newcastle disease antibody titer of laying hens.
国家科技期刊平台
NSTL
万方数据
维普
