Effect of Bacteroides on liver lipid metabolism of laying hens with fatty liver hemorrhage syndrome induced by high energy and low protein diet
The purpose of the study was to investigate the effect of Bacteroides on liver lipid metabolism in laying hens with fatty liver hemorrhage syndrome(FLHS)induced by high-energy and low-protein diet.Eighty 210-day-old Dawu Jinfeng laying hens weighing(1.5±0.2)kg were randomly divided into four groups with five replicates in each group and four hens in each replicate.The control group(Group C)was fed with basal diet,the model group(Group M)was fed with high energy and low protein(HELP)diet,the low dose Bacteroides group(Group BL)was fed with HELP diet+1 × 109 CFU/mL Bacteroides,and the high dose Bacteroides group(Group BH)was fed with HELP diet+1 × 1011 CFU/mL Bacteroides.The trial period was 70 days.The results showed that compared with Group C,the liver of Group M was greasy,brittle and fragile,with a large number of fat vacuoles and red-stained fat droplets,the liver index and abdominal fat rate increased significantly(P＜0.05),and the serum TG,TC,LDL-C concentrations and AST,ALT activities increased significantly(P＜0.05),while HDL-C concentration decreased significantly(P＜0.05).Compared with Group M,Group BL and Group BH showed significant improvement in liver fat vacuoles and red stained lipid droplets in laying hens,the liver index significantly decreased(P＜0.05),the levels of serum TG,TC,LDL-C,as well as the activities of AST and ALT,were significantly reduced(P＜0.05),while the levels of HDL-C were significantly increased(P＜0.05).Compared with Group BH,serum TG,TC concentrations and AST activity in BL group decreased significantly(P＜0.05),while HDL-C concentration increased significantly(P＜0.05).Study shows that Bacteroides can improve lipid metabolism disorder and liver function damage caused by FLHS.Bacteroides with 1 × 109 CFU/mL is more effective in regulating liver lipid metabolism in FLHS laying hens.
国家科技期刊平台
NSTL
万方数据
维普
