The experiment aimed to study the impact of traditional Chinese medicine compound polysaccharides on the growth performance,immune moderation,and intestinal flora of broilers.A total of 900 1-day-old broilers were selected.The broilers in the blank control group(BCG)were fed a basal diet,and those in the positive control group(PCG)were fed a basal diet supplemented with 10 mg/kg levamisole hydrochloride,and those in different concentrations of TCMCP groups(0.5％,1.0％,and 2.0％TCMCPG)were fed a basal diet supplemented with 0.5％,1.0％,and 2.0％TCMCP.There were 3 replicates in each group and 60 broilers in each replicate.The experiment lasted for 42 days.The results showed that the final weight of 0.5％,1.0％,and 2.0％TCMCPG groups was extremely higher than the BCG group(P＜0.01).1.0％TCMCPG group extremely increased average daily gain(P＜0.01),0.5％and 2.0％TCMCPG groups significantly increased average daily gain(P＜0.05).The ratio of feed to gain in 0.5％,1.0％and 2.0％TCMCPG groups was extremely decreased(P＜0.01).Serum immunoglobulin G(IgG)content in 1.0％and 2.0％TCMCPG groups was extremely higher than the BCG group(P＜0.0l),and serum IgG content in 0.5％TCMCPG group was significantly increased(P＜0.05).1.0％TCMCPG group extremely increased the content of immunoglobulin A(IgA)(P＜0.01).Serum immunoglobulin M(IgM)content in 1.0％and 2.0％TCMCPG groups was significantly increased(P＜0.05).In 0.5％,1.0％and 2.0％TCMCPG groups,thymus,bursa,and spleen indexes were extremely increased(P＜0.01),and serum concentrations of interleukin-2(IL-2),interleukin-4(IL-4),and interferon-y(IFN-γ)were extremely increased(P＜0.01).The number and volume of lymphocytes in the splenic tissue structure increased.In terms of intestinal flora,0.5％,1.0％and 2.0％TCMCPG groups extremely decreased the number of Escherichia coli in jejunum and cecum(P＜0.01),and extremely increased the number of Lactobacillus in cecum(P＜0.01).The Lactobacillus number in jejunum was extremely increased in 1.0％TCMCPG group(P＜0.0l).The study indicates that TCMCP can improve the immune function,improve the enteric microbiome,and improve growth performance,1.0％TCMCPG has the best effect.
traditional Chinese medicine compound polysaccharidebroilersgrowth performanceimmune functionintestinal flora
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