首页|益生菌对免疫的调节作用及对肠-肺轴的影响

益生菌对免疫的调节作用及对肠-肺轴的影响

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益生菌在改善畜禽健康水平,提高生产性能,无抗绿色养殖等方面发挥重要作用.益生菌能够通过调节细胞信号因子和免疫信号通路来参与免疫调节,进而改善黏膜免疫系统的生理机能,影响宿主健康.肠道微生物区系与黏膜免疫系统联系密切,肠道和肺部通过肠-肺轴的微生物区系和免疫系统实现双向调节.益生菌在预防和治疗胃肠道及呼吸系统疾病等方面具有较大潜力.因此,对益生菌与肠道菌群、黏膜免疫调节的相互作用机制进行深入了解,有利于其在动物生产中的应用.文章对益生菌与肠道微生物区系和免疫调节的关系及益生菌对肠-肺轴的影响进行综述,以期为益生菌的深入研究和广泛应用提供参考.
Modulatory effect of probiotics on immunity and its effect on the gut-lung axis
Probiotics play an important role in improving the health level of livestock and poultry,improving production performance,and antibiotic-free green farming.Probiotics can participate in immune regulation by regulating cell signaling factors and immune signaling pathways,thereby improving the physiological functions of the mucosal immune system to affect the health of the host.The intestinal microbiota is closely related to the mucosal immune system,and the intestine and lungs achieve two-way regulation through the interaction of microflora and immune regulation,which is called the gut-lung axis.Probiotics have considerable potential in the prevention and treatment of gastrointestinal and respiratory diseases,so it is necessary to have an in-depth understanding of the interaction mechanism between probiotics and intestinal microbiota and mucosal immunomodulation,so as to facilitate their application in animals production.In this paper,the relationship between probiotics and intestinal microflora and immune regulation in animals and the effect of probiotics on the gut-lung axis are discussed,in order to provide reference for the in-depth research and wide application of probiotics.

probioticsimmunitygut-lung axis

赵蕾蕾、魏娜、张嵘、杨小勇、董延江、吴倩、刘洋

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爱普罗斯科创(辽宁)有限公司,辽宁 沈阳 110064

沈阳药科大学,辽宁 沈阳 110016

山东康益健生物科技有限公司,山东 济宁 273500

辽宁省农业发展服务中心,辽宁 沈阳 110003

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益生菌 免疫 肠-肺轴

2024

饲料研究
北京市营养源研究所

饲料研究

CSTPCD北大核心
影响因子:0.391
ISSN:1002-2813
年,卷(期):2024.47(22)