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数智中医(闻)嗅诊研究进展

Research progress on olfactory diagnosis of smart traditional Chinese medicine

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嗅诊是中医"望、闻、问、切"四诊中"闻诊"的重要组成部分,通过辨气味诊察疾病、区分证型.虽然嗅诊在中医临床应用中有着悠久的历史,但其客观化、标准化仍是亟待解决的问题.近年来,随着分析化学、生物医学工程、人工智能等领域的迅猛发展,中医进入"数智化"发展新时代,这同时也促使嗅诊作为一种无创诊断方法愈发受到重视.本文对数智中医(闻)嗅诊的研究进展进行了综述,归纳了数智中医嗅诊研究对象、分析方法和科学仪器,概述了相关临床应用,总结了目前存在的挑战,并对中医智能(闻)嗅诊巨大的研究价值以及未来的发展进行了展望.
Olfactory diagnosis is an important part of the"listening and smell diagnosis"in the four diagnostics of traditional Chinese medicine(TCM)—Inspection,listening/smell,inquiring,and palpation.It differentiates diseases and TCM syndromes by identifying smells.Olfactory diagnosis has a long history in the clinical application of TCM.However,the objectification and standardization of olfactory diagnosis are urgently needed.Embracing the tremendous progress in the fields of analytical chemistry,biomedical engineering and artificial intelligence,TCM has stepped into the"smart"era.This has been contributing to the growing interest in olfactory diagnosis as a non-invasive diagnostic method.This paper provides a review of the research progress in olfactory diagnosis of smart TCM.The research subjects,analytical methods,and scientific instruments of olfactory diagnosis of smart TCM were summarized,the relevant medical applications were outlined,and the current challenges were proposed.The great research value of olfactory diagnosis of smart TCM as well as its future development is also envisioned.

Digital-intelligence traditional Chinese medicineOlfactory diagnosisVolatile organic compoundsExhaled breath analysisInstruments for traditional Chinese medicine diagnosis and treatmentDisease diagnosis

张玫、钟瑞、魏旭煦、张晓雨、代倩倩、林家燕、赵晨、蒋寅、商洪才

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北京中医药大学中药学院(北京 102488)

北京中医药大学东直门医院中医内科学教育部/北京市重点实验室(北京 100700)

中国中医科学院中医临床基础医学研究所(北京 100700)

数智中医 嗅诊 挥发性有机物 呼出气分析 中医诊疗仪器 疾病诊断

国家重点研发计划"中医药现代化"重点专项国家重点研发计划"中医药现代化"重点专项北京市自然科学基金

2022YFC35023002022YFC3502305L222150

2024

10.12173/j.issn.1004-4337.202401029

数理医药学杂志
武汉大学,中国工业与应用数学学会,医药数学专业委员会

数理医药学杂志

影响因子：0.479
ISSN：1004-4337
年,卷(期)：2024.37(1)
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