Ovarian cancer(OC)is one of the three common primary malignant tumors in women,which seriously endangers the reproductive health.Due to its high concealment,susceptibility to drug resistance,and susceptibility to recurrence,the prognosis of patients is poor and the mortality rate is extremely high.MicroRNA(miRNA)is a type of small molecule single stranded non coding RNA that primarily exerts gene expression regulation at the post transcriptional level by specifically inhibiting translation or degrading target mRNA.Multiple miRNAs have been confirmed to be abnormally expressed in OC and play a core role in regulating cell migration and invasion,drug resistance,angiogenesis,and tumor microenvironment.This article reviews the biological functions of miRNA and its role in OC,in order to provide references for the diagnosis,treatment,prognosis and intervention targets of OC.
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