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中国儿童青少年代谢综合征患病率的Meta分析

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目的 通过Meta分析系统评价中国儿童青少年代谢综合征(metabolic syndrome,MS)的流行现状,为其早期防治干预提供参考.方法 在中国知网、万方、中国生物医学文献数据库(CBM)、中华医学期刊全文数据库、PubMed、Embase和the Cochrane Library中检索中国儿童青少年MS患病率及流行病学相关研究,检索时限为建库至2024年2月1日.按照预先制定的纳入和排除标准进行文献筛选、数据提取,采用乔安娜布里格斯研究所(Joanna Briggs Institute,JBI)评价工具进行文献质量评价.采用Review Manager 5.4.1软件进行统计学分析,并对性别、体重、年龄等因素进行亚组分析.结果 共纳入28篇文献,其中中文文献24篇、英文文献4篇.依据Cook标准、中国儿童青少年代谢综合征定义和防治建议(CHN2012)标准、国际糖尿病联盟(International Diabetes Federation,IDF)标准,中国儿童青少年MS患病率分别为5%、4%及3%.按照3种诊断标准,MS患病率均表现为男生>女生、肥胖组>超重组>正常组.结论 儿童青少年MS在我国呈流行趋势,超重和肥胖是MS的重要危险因素,男生较女生更容易患MS,因此应对儿童青少年超重、肥胖问题采取积极干预措施,同时重点关注男生MS相关指标的情况,以控制MS的发生.
Prevalence of metabolic syndrome in Chinese children and adolescents:a Meta-analysis
Objective To systematically evaluate the prevalence of metabolic syndrome(MS)in Chinese children and adolescents through Meta-analysis,in order to provide reference for early prevention and treatment of MS.Methods CNKI,Wanfang Data,CBM,Full-text Database of Chinese Medical Journal,PubMed,Embase and the Cochrane Library were searched for relevent studies on the prevalence and epidemiology of MS in Chinese children and adolescents from the establishment of the databases to February 1,2024.Literature screening and data extraction were conducted based on pre-established inclusion and exclusion criteria.The quality of literature was evaluated using the Joanna Briggs Institute(JBI)evaluation tool.Statistical analysis was performed using Review Manager 5.4.1 software with subgroup analysis considering factors such as gender,weight,age etc.Results A total of 28 articles were included,including 24 Chinese articles and 4 English articles.According to Cook standard,the definition and prevention recommends of metabolic syndrome in Chinese children and adolescents(CHN2012)standard,and International Diabetes Federation(IDF)standard,the prevalence rates of MS in Chinese children and adolescents were 5%,4%and 3%,respectively.According to the three diagnostic criteria,the prevalence rate of MS was higher in boys than girls,and higher in the obese group and overweight group compared to the normal group.Conclusion Overweight and obesity were significant risk factors for MS in Chinese children and adolescents.Boys were more susceptible to MS than girls.Therefore,active intervention measures should be taken for overweight and obesity in children and adolescents,while focusing on relevant indicators for boys'MS,in order to control the occurrence of MS.

Metabolic syndromeChildren and adolescentsPrevalenceMeta-analysis

高雨霏、张力之、朱文萱、吴娜、李光萍、郭思思、宋花玲

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上海中医药大学公共健康学院(上海 201203)

上海中医药大学附属宝山医院体检中心(上海 201999)

代谢综合征 儿童青少年 患病率 Meta分析

2024

数理医药学杂志
武汉大学,中国工业与应用数学学会,医药数学专业委员会

数理医药学杂志

影响因子:0.479
ISSN:1004-4337
年,卷(期):2024.37(12)