Synthesis of 2,2,6,6-Tetramethyl-4-Piperidyl 3-Phenylacrylate as Piperidine Alcohol Benzoate
3-phenylacrylic acid(2,2,6,6-tetramethyl-4-hydroxypiperidine)ester was synthesized using 3-phenylacrylic acid methyl ester and 2,2,6,6-tetramethyl-4-hydroxypiperidine as raw materials under the action of solvents and catalysts.We studied how the product yield was affected by such factors as reaction time,solvent and catalyst type and amount,as well as raw material ratio.The results showed that under the optimized reaction conditions,tetrabutyl titanate was used as a catalyst,petroleum ether was used as a solvent,n(methyl 3-phenylacrylate)∶n(2,2,6,6-tetramethyl-4-piperidinol)∶n(petroleum ether)∶n(tetrabutyl titanate)=1∶1.15∶2.47∶0.05,reaction temperature was 120-125℃and reaction time was 8 hrs.,and the yield rate of product reached 96.09%.
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