Research progress in clinical application of urinary microalbumin creatinine ratio in children with kidney disease
Urinary microalbumin creatinine ratio(UMACR)is characterized by higher sensitivity,stronger stability and more convenient to be detected,which is best correlated with 24 h urinary albumin quantification.In the early stages of a variety of kidney diseases in children without obvious lesions,UMACR can detect subtle changes in renal function in a timely manner,thus avoiding its progression and deterioration.UMACR is a good early predictor and screening factor for these diseases.However,due to the limitation of research quality and quantity,and the difference between detection methods,age and other factors,there is no uniform reference interval for UMACR in children,UMACR is not recommended by pediatric consensus and guidelines.The reference intervals used by domestic and foreign scholars are uneven,which affects the reference value of the research results to a certain extent.This review summarizes the reference interval of UMACR for children,the clinical application of UMACR for children with kidney disease and its shortcomings,in order to provide reference for early identification and active intervention of potential children with kidney disease.
万方数据
维普
