Role and molecular mechanism of STC1 in reproduction-related tumors
Stanniocalcin 1(STC1)is a glycoprotein hormone that regulates plasma calcium and phosphorus balance.Previous studies on STC1 mostly focused on calcium and phosphorus balance,oxidative stress,inflammatory response,etc.Recent studies have found that STC1 plays an important role in tumorigenesis,growth,proliferation,apoptosis,invasion and metastasis of tumors.This paper reviews the expression of STC1,its mechanism and its relationship with tumor prognosis in the reproductive-related tumors,such as breast cancer,ovarian cancer,cervical cancer,prostate cancer and bladder cancer,to provide new ideas for tumor treatment.
stanniocalcin 1reproductive-related tumorstumorigenesis and developmentpoor prognosis
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