首页|酸性哺乳动物几丁质酶的研究进展

酸性哺乳动物几丁质酶的研究进展

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酸性哺乳动物几丁质酶是食用燕窝中普遍且大量存在的活性蛋白质之一,是哺乳动物中常见的几丁质酶,能够在酸性环境下保持活性并水解几丁质.酸性哺乳动物几丁质酶主要在人体的呼吸系统和消化系统中表达,且在多种病理机制和免疫炎症中有调节作用.本文综述了酸性哺乳动物几丁质酶的理化性质与功能,包括其在人体各个系统和器官中发挥的多种作用及相关机制,以探究其对人类健康和疾病的影响.
Research progress on acidic mammalian chitinase
Acidic mammalian chitinase is one of the most common and abundant active proteins in edible bird's nest.It is a common chitinase in mammals and can maintain its activity and hydrolyze chitin under acidic environment.Acidic mammalian chitinase is mainly expressed in human respiratory system and digestive system.It plays a regulatory role in a variety of pathological mechanisms and immune inflammation.This paper reviews the physicochemical properties and functions of acidic mammalian chitinase,including its multiple functions and related mechanisms in various systems and organs of the human body,in order to explore its impact on human health and disease.

acidic mammalian chitinasechitinphysicochemical propertiesactivity

袁满、林小仙、张新科、王东亮

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北京小仙炖生物科技有限公司,北京 100020

河北省燕窝鲜炖技术创新中心,廊坊 065700

山东大学齐鲁医学院药学院新药药理研究所,天然产物教育部重点实验室,济南 250012

酸性哺乳动物几丁质酶 几丁质 理化性质 活性

国家自然科学基金面上项目

82273835

2023

生命的化学
中国生物化学与分子生物学会

生命的化学

CSTPCD
影响因子:0.404
ISSN:1000-1336
年,卷(期):2023.43(1)
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